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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >The dynamics of word retrieval in major depression.
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The dynamics of word retrieval in major depression.

机译：重症抑郁症词检索的动态。

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Impairment in the retrieval of specific episodes from autobiographical memory is commonly observed in major depression. However, it is unclear whether impairment in retrieval processes is a general characteristic of major depression or is confined to the recollection of personal memories. This study examined the time course of the retrieval of words from semantic memory.A letter fluency test was administered to 65 inpatients with major depression and 50 healthy controls. A two-parameter model was fit to the decay curve representing the production of words over a 90-second period. One parameter, N, is an estimate of the total number of words that would be generated if the respondent was given unlimited time. The other, tau, is the average of the difference in time between the first word generated and each subsequent word.There was evidence of a deficit in the retrieval of words from long-term memory in depressed patients. The significant difference between groups suggested that even if given an extended period of time in which to respond to compensate for possible slowness, the depressed group would not retrieve as many words as the controls. The retrieval failure could not be attributed solely to cognitive slowing or the effects of antidepressant medication.The results extend findings of a deficit in the process of retrieving specific episodes from autobiographical memory and suggest that a generalised impairment in memory retrieval may be characteristic of major depression.
机译：在重大抑郁症中通常观察到自传记忆中特定发作检索的损伤。然而，目前尚不清楚检索过程中的损伤是主要抑郁症的一般特征，也不是局限于个人记忆的回忆。本研究检测了从语义记忆中检索单词的时间过程。用重度抑郁和50个健康对照给65名住院患者给出字母流量试验。两个参数模型适合衰减曲线，表示在90秒的时间内产生的单词。一个参数n，是如果被访者提供无限时间，则会估计会产生的单词总数。另一个，Tau，是生成的第一单词与每个后续单词之间的时间差的平均值。有证据表明抑郁症患者的长期记忆中的单词赤字。组之间的显着差异表明，即使给出了响应赔偿可能缓慢的延长时间的延长时间，抑郁群将不会检索为控制的许多单词。检索失败不能仅归因于认知减缓或抗抑郁药物的影响。结果延长了从自传记忆中检索特定发作过程中的赤字的结果，并表明内存检索中的广义损害可能是重大抑郁的特征。

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