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首页> 外文期刊>The British Journal of Nutrition >Abomasally infused SFA with varying chain length differently affect milk production and composition and alter hepatic and mammary gene expression in lactating cows
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Abomasally infused SFA with varying chain length differently affect milk production and composition and alter hepatic and mammary gene expression in lactating cows

机译:具有不同链条长度的草瘤注入的SFA不同地影响牛奶生产和组成,并改变哺乳酸奶牛中的肝癌和乳腺基因表达

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The aim of the present study was to compare the effects of post-ruminally infused fat supplements, varying in fatty acid (FA) chain length, on animal performance, metabolism and milk FA. Eleven multiparous Holstein dairy cows were used in a replicated incomplete 3 x 3 Latin square design with 7-d periods, separated by 7-d washouts. Treatments were administered as abomasal infusions of enrichments providing 280 g/d of FA: (1) palmitic acid (98 center dot 4 % 16 : 0; PA), (2) caprylic and capric acids (56 center dot 2 % 8 : 0, 43 center dot 8 % 10 : 0; medium-chain TAG (MCT)) and (3) stearic acid (99 center dot 0 % 18 : 0; SA). Relative to PA, SA decreased the efficiency of fat-corrected milk production, which was associated with a tendency for higher DM intake and lower FA absorption with SA, whereas MCT was not different from PA for these variables. Milk fat concentration and yield were increased by PA relative to SA, but only fat yield tended to be greater relative to MCT. Relative to PA, MCT increased milk fat concentration of FA < 16 C, whereas SA increased FA > 16 C. Expression of mammary stearoyl-coA desaturase 1 was lower with SA than with PA. Relative to PA, liver expression of adenosine monophosphate-activated protein kinase-1 and pyruvate kinase was increased with MCT, whereas expression of these genes tended to be increased by SA. The mechanism of increased fat secretion with PA does not seem to be related to a modulation of the expression of lipogenesis-related genes, but rather to increased substrate availability as reflected by milk FA profile.
机译:本研究的目的是比较仪式中注入的脂肪补充剂,在脂肪酸(FA)链长,对动物性能,代谢和牛奶FA之间的影响进行比较。 11个多个多数荷斯坦乳制品奶牛用7-D次,用7-D垫子分开的7-D次,以7-D型张开,以7-D浅滩使用。作为富集的富集的富集输注给予治疗:(1)棕榈酸(98中心点4%16:0; PA),(2)毛细管和癸酸(56中心点2%8:0 ,43中心点8%10:0;中链标签(MCT))和(3)硬脂酸(99中心点0%18:0; SA)。相对于PA,SA降低了脂肪校正的牛奶产量的效率,其与较高DM摄入量的趋势与SA较低的FA吸收相关,而MCT与这些变量的PA没有不同。 PA相对于SA通过PA增加牛奶脂肪浓度和产率,但只有脂肪产率相对于MCT更大。相对于PA,MCT增加了FA <16 C的乳脂浓度,而SA增加了Fa> 16℃。乳腺素硬币-CoA去饱和酶1的表达与SA低于PA。相对于PA,随着MCT增加了腺苷活化蛋白激酶-1和丙酮酸激酶的肝脏表达,而这些基因的表达倾向于通过SA增加。增加脂肪分泌的机制似乎与脂肪生成相关基因表达的调节似乎没有相关,而是增加由牛奶FA轮廓反射的基底可用性。

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