miRNA expression for early diagnosis of preeclampsia onset: hope or hype?

Lagana Antonio Simone; Vitale Salvatore Giovanni; Sapia Fabrizio; Valenti Gaetano; Corrado Francesco; Padula Francesco; Rapisarda Agnese Maria Chiara; DAnna Rosario

首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >miRNA expression for early diagnosis of preeclampsia onset: hope or hype?

【24h】

miRNA expression for early diagnosis of preeclampsia onset: hope or hype?

机译：MiRNA表达早期诊断Preclampsia发作：希望或炒作？

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Purpose: Preeclampsia (PE) is a multi-systemic disease characterized by hypertension, proteinuria and other typical signs that can negatively affect the development of pregnancy. The outcome of the disease is strongly linked to the possibility of early diagnosis, in order to prevent the clinical manifestations. Pathogenesis is still unknown, although abnormalities of placenta development linked to angiogenesis alterations and abnormal trophoblastic invasion seem to be involved, corroborating the epigenetic theory. Basing on these elements, this review aims to summarize the possible role of miRNAs in PE onset, both as increased or decreased expression in placenta or as maternal serum markers.

机译：目的：预口度（PE）是一种以高血压，蛋白尿和其他典型迹象为特征的多全身性疾病，可对妊娠的发展产生负面影响。疾病的结果与早期诊断的可能性强烈相关，以防止临床表现。发病机制仍然是未知的，尽管胎盘发展的异常与血管生成改变和异常的滋养细胞侵袭有关，但是涉及介绍表观遗传理论。基于这些要素，本综述旨在总结MiRNA在PE发作中的可能作用，胎盘或胎儿表达的增加或母体血清标志物。

著录项

来源
《The journal of maternal-fetal & neonatal medicine》 |2018年第6期|共5页
作者
Lagana Antonio Simone; Vitale Salvatore Giovanni; Sapia Fabrizio; Valenti Gaetano; Corrado Francesco; Padula Francesco; Rapisarda Agnese Maria Chiara; DAnna Rosario;
展开▼
作者单位

Univ Messina Dept Human Pathol Adulthood &

Childhood G Barresi Unit Gynecol &

Obstet Via C;

Univ Messina Dept Human Pathol Adulthood &

Childhood G Barresi Unit Gynecol &

Obstet Via C;

Univ Catania Dept Gen Surg &

Med Surg Specialties Catania Italy;

Univ Catania Dept Gen Surg &

Med Surg Specialties Catania Italy;

Univ Messina Dept Human Pathol Adulthood &

Childhood G Barresi Unit Gynecol &

Obstet Via C;

Altamed Fetal Maternal Med Ctr Dept Obstet &

Gynecol Ultrasound Rome Italy;

Univ Catania Dept Gen Surg &

Med Surg Specialties Catania Italy;

Univ Messina Dept Human Pathol Adulthood &

Childhood G Barresi Unit Gynecol &

Obstet Via C;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类产科学;
关键词
Preeclampsia; miRNAs; epigenetics; early diagnosis; outcomes;

机译：Preclampsia;miRNA;表观生物学;早期诊断;结果;

相似文献

外文文献
中文文献
专利

1. miRNA expression for early diagnosis of preeclampsia onset: hope or hype? [J] . Lagana Antonio Simone, Vitale Salvatore Giovanni, Sapia Fabrizio, The journal of maternal-fetal & neonatal medicine . 2018,第1a6期

机译：MiRNA表达早期诊断Preclampsia发作：希望或炒作？
2. Differential expression of miRNAs are associated with the insulin signaling pathway in preeclampsia and gestational hypertension [J] . Khaliq Olive P., Murugesan Saravanakumar, Moodley Jagidesa, Clinical and experimental hypertension: CEH . 2018,第5a8期

机译：miRNA的差异表达与先兆子痫和妊娠期高血压中的胰岛素信号通路相关联
3. MiRNA-QC-and-Diagnosis: An R package for diagnosis based on MiRNA expression [J] . Michele Castelluzzo, Alessio Perinelli, Simone Detassis, SoftwareX . 2020,第2期

机译：miRNA-qc-and诊断：基于miRNA表达的诊断R包
4. Classification of miRNA Expression Data Using Random Forests for Cancer Diagnosis [C] . Eliza Razak, Faridah Yusof, Raha Ahmad Raus International conference on computer and communication engineering . 2016

机译：使用随机森林对miRNA表达数据进行分类以进行癌症诊断
5. Modulation of Microrna Expressions in Tomato by Short Tandem Target Mimic and Artificial MiRNAs [D] . Liu, Haiping. 2017

机译：短串联靶模模仿番茄中微小RNA表达的调节
6. Association of Circulating miRNA Expression with Preeclampsia Its Onset and Severity [O] . Zuzana Kolkova, Veronika Holubekova, Marian Grendar, 2021

机译：循环miRNA表达与先兆子痫其发病和严重程度
7. Association of Circulating miRNA Expression with Preeclampsia, Its Onset, and Severity [O] . Zuzana Kolkova, Veronika Holubekova, Marian Grendar, 2021

机译：循环miRNA表达与先兆子痫，其发病和严重程度

miRNA expression for early diagnosis of preeclampsia onset: hope or hype?

摘要

著录项

相似文献

相关主题

期刊订阅