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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Levels of multiple proteins in gingival crevicular fluid and intra-amniotic complications in women with preterm prelabor rupture of membranes
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Levels of multiple proteins in gingival crevicular fluid and intra-amniotic complications in women with preterm prelabor rupture of membranes

机译：用早产预防膜破裂的女性牙龈颈渗透液和羊膜内并发症中多种蛋白质的水平

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Objective: The primary aim of this study was to identify the association between the local inflammatory response in gingival crevicular fluid measured by the levels of multiple proteins and maternal and intra-amniotic inflammatory responses measured by maternal serum C-reactive protein (CRP) and amniotic fluid interleukin (IL)-6 concentrations, respectively, in women with preterm prelabor rupture of membranes (PPROM). Methods: A prospective study was performed in which 78 women with singleton pregnancies complicated by PPROM between 24 + 0 and 36 + 6 weeks of gestation were included. Transabdominal amniocenteses were performed at the time of admission. A bedside assessment of amniotic fluid IL-6 was performed. Maternal serum CRP concentration was also measured at the time of admission. Gingival crevicular fluid was collected from the pocket of the selected tooth (the tooth with the deepest pocket) using standard sterile paper strips within 72 h after admission. Twenty-six proteins in the gingival crevicular fluid were assessed by multiplex the Meso-Scale technology.
机译：目的：本研究的主要目的是鉴定由母体血清C-反应蛋白（CRP）和羊膜（CRP）测量的多种蛋白质和羊膜内炎症反应的水平测量的牙龈沟槽局部炎症反应之间的关联分别在具有早产预防膜（PPROM）的女性中的液体白细胞介素（IL）-6浓度。方法：进行了一项前瞻性研究，其中包括在妊娠24℃和36 + 6周之间复杂的PPROM复杂的78名妇女。在入院时进行Transabominal amniocenteses。进行羊水IL-6的床头算法。在入院时也测量母体血清CRP浓度。使用标准无菌纸条在入院后72小时内从所选牙齿（牙齿的牙齿）的袋中收集牙龈沟槽。通过复用中间级技术评估牙龈沟槽中的26例蛋白。

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