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首页> 外文期刊>AIDS care. >The risk of HIV and HCV infections among injection drug users in northeast India.
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The risk of HIV and HCV infections among injection drug users in northeast India.

机译:印度东北部注射毒品使用者中HIV和HCV感染的风险。

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摘要

Injection drug users (IDUs) and their associated risk behavior are responsible for driving the human immunodeficiency virus (HIV) epidemic in northeast India. So a group of IDUs from two northeastern states (Mizoram and Nagaland) of India were studied to find the prevalence of HIV, co-infection with hepatitis C virus (HCV), hepatitis B virus (HBV), and associated risk behaviors. Out of the 400 IDUs enrolled, 398 consented for HIV, HCV, and hepatitis B surface antigen (HbsAg) test. Of them, 10.8% were HIV-1 antibody positive, 47.8% had HCV antibody, and 3.8% had detectable HBsAg. Among the HIV infected subjects, 79.1% were co-infected with HCV and 6.9% had triple infection. Heroin users showed a higher association with HIV (OR = 7.3, 95% CI: 2.5-21.5, p=0.0003) and HCV infection (OR = 7.6, 95% CI: 3.5-16.6, p<0.0001) than Spasmo-proxyvon (dextropropoxyphene, a synthetic opiod analgesic). In summary, apart from the known risk variables among IDUs, type of injecting drugs also influences the HIV/HCV transmission pattern among the IDUs.
机译:注射毒品使用者(IDU)及其相关的危险行为是导致印度东北部人类免疫缺陷病毒(HIV)流行的原因。因此,对印度东北两个州(米佐拉姆邦和那加兰邦)的一组吸毒者进行了研究,以发现艾滋病毒的流行率,丙型肝炎病毒(HCV),乙型肝炎病毒(HBV)的共同感染以及相关的危险行为。在登记的400个IDU中,有398个同意接受HIV,HCV和乙型肝炎表面抗原(HbsAg)测试。其中,HIV-1抗体阳性率为10.8%,HCV抗体为47.8%,可检测到的HBsAg为3.8%。在感染了HIV的受试者中,有79.1%与HCV共同感染,而6.9%有三重感染。海洛因使用者显示出与Spasmo-proxyvon(OR = 7.3,95%CI:2.5-21.5,p = 0.0003)和HCV感染(OR = 7.6,95%CI:3.5-16.6,p <0.0001)的关联性更高(Spasmo-proxyvon(右旋丙氧芬(一种合成的阿片类镇痛药)。总之,除了注射毒品使用者之间已知的风险变量外,注射药物的类型还影响注射毒品使用者之间的HIV / HCV传播方式。

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