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首页> 外文期刊>AIDS care. >Disability and HIV: A systematic review and a meta-analysis of the risk of HIV infection among adults with disabilities in Sub-Saharan Africa
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Disability and HIV: A systematic review and a meta-analysis of the risk of HIV infection among adults with disabilities in Sub-Saharan Africa

机译：残疾与艾滋病毒：撒哈拉以南非洲残疾成年人中艾滋病毒感染风险的系统评价和荟萃分析

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More than one billion people worldwide are estimated to be living with a disability. A significant proportion of them lives in Sub-Saharan Africa where they are reported to be at increased risk of HIV. However, quantitative evidence on this remains scarce. A systematic review and a meta-analysis of the risk of HIV infection among people with disabilities living in Sub-Saharan Africa were undertaken. We searched all published or unpublished studies and national surveys reporting HIV prevalence among adults with disabilities living in Sub-Saharan Africa between 2000 and 2013. The risk ratio (RR) of HIV infection in people with disabilities versus people without disabilities was estimated through a random-effects meta-analysis. Of the 12,252 references screened, 13 studies were selected. HIV prevalence varied widely across studies from 1.1% to 29%. Pooled RRs of HIV infection in people with disabilities compared to the general population were 1.31 (1.02-1.69) overall; 1.16 (0.71-1.87) among people with mental illness or intellectual disabilities and 1.07 (0.58-1.95) among people with hearing disabilities. This meta-analysis provides evidence that people with disabilities do not have a lower risk of HIV when compared to the general population, and that women with disabilities are especially affected. A clear increasing gradient in the risk of HIV according to gender and disability status was also observed. The important heterogeneity across studies and their varying quality warrant a closer look at the intersection between disability and HIV. Additional studies with more systematic approaches and with higher-quality methodologies are required to further address this knowledge gap.
机译：据估计，全世界有超过十亿的残疾人。他们中的很大一部分生活在撒哈拉以南非洲，据报告他们感染艾滋病毒的风险增加。但是，对此的定量证据仍然很少。对居住在撒哈拉以南非洲地区的残疾人的艾滋病毒感染风险进行了系统的审查和荟萃分析。我们搜索了所有发表或未发表的研究和国家调查，这些研究和国家调查报告了2000年至2013年间居住在撒哈拉以南非洲地区的残疾成年人中的艾滋病毒流行率。通过随机估算了残疾人与残疾人之间艾滋病毒感染的风险比（RR） -荟萃分析。在筛选的12,252篇参考文献中，选择了13项研究。整个研究中，艾滋病毒感染率差异很大，从1.1％到29％。与一般人群相比，残疾人感染艾滋病毒的汇总RR为1.31（1.02-1.69）。患有精神疾病或智力障碍的人中的比例为1.16（0.71-1.87），患有听力障碍的人中的比例为1.07（0.58-1.95）。这项荟萃分析提供的证据表明，与普通人群相比，残疾人感染艾滋病毒的风险并不低，而且残疾妇女尤其受到影响。还观察到根据性别和残疾状况，艾滋病毒感染风险明显增加。研究之间重要的异质性及其不同的质量，需要仔细研究残疾与HIV之间的交集。需要用更系统的方法和更高质量的方法进行其他研究，以进一步解决这一知识鸿沟。

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