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Adherence to antiretroviral therapy in rural persons living with HIV disease in the United States.

机译:在美国,农村艾滋病毒感染者坚持抗逆转录病毒疗法。

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The current study delineated patterns and predictors of adherence to antiretroviral therapy in 329 persons living with HIV disease in rural areas of 12 US states. Participants provided self-report data on patterns of HIV medication adherence, reasons for missing medication doses, psychological symptomatology, life-stressor burden, social support, ways of coping, coping self-efficacy, the quality of their relationship with their main physician, and barriers to health care and social services. Based on adherence data collected via retrospective, self-report assessment instruments, only 50% of participants adhered consistently to antiretroviral therapy regimens in the past week. Consistent adherence was more common in White participants, persons who had progressed to AIDS, and 'native infections' (i.e. persons who were born, raised, and infected in their current place of residence). Logistic regression analyses indicated that consistent adherence was reported by persons who drank less alcohol, had a good relationship with their main physician, and engaged in more active coping in response to HIV-related life stressors. As the number of rural persons living with HIV disease continues to increase, research that identifies correlates of non-adherence and conceptualizes approaches to optimize adherence in this group is urgently needed.
机译:当前的研究描述了美国12个州农村地区329名艾滋病毒感染者坚持抗逆转录病毒疗法的方式和预测因素。参与者提供了有关HIV药物依从性模式,药物剂量缺失的原因,心理症状,生活压力负担,社会支持,应对方式,应对自我效能,与主治医生的关系质量的自我报告数据,以及卫生保健和社会服务的障碍。根据通过回顾性自我报告评估工具收集的依从性数据,在过去一周中,只有50%的参与者始终坚持抗逆转录病毒疗法。在白人参与者,已发展成艾滋病的人和“原住民感染”(即在其当前居住地出生,成长和感染的人)中,坚持服药更为普遍。 Logistic回归分析表明,喝酒少,与主治医生有良好关系,并应对HIV相关的生活压力源而采取更积极的应对措施的人报告了坚持治疗的情况。随着农村地区感染艾滋病毒的人数不断增加,迫切需要进行研究,以查明不依从性的相关因素,并对这一群体中依从性进行优化的方法进行概念化。

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