...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Accuracy of estimating resting oxygen uptake and implications for hemodynamic assessment
【24h】

Accuracy of estimating resting oxygen uptake and implications for hemodynamic assessment

机译：估算休息氧气吸收的准确性及血液动力学评估的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The Fick principle (cardiac output [Q c] = oxygen uptake [Vo 2]/arteriovenous oxygen difference) can be used to calculate Q c, with VO 2 frequently estimated by derived equations. To compare the accuracy of measured versus estimated VO 2, data were analyzed from 2 studies in which VO 2 at rest was measured using the Douglas bag technique. One study comprised adults with diabetes, and the other was an exercise study of healthy adults. VO 2 at rest was estimated as VO 2 (ml/min) = 125 ml/min/m 2 × body surface area (m 2), with sensitivity analyses evaluating 2 other commonly used equations. Mean absolute difference (milliliters per minute) and ordinary least products regression were used to assess agreement between measured and estimated VO 2. Overall, mean measured versus estimated VO 2 differed significantly (307.2 ± 75.2 vs 259.9 ± 36.7 ml/min, p 0.0001), with a mean absolute difference of 52.9 ± 43.2 ml/min (p 0.0001); 20% of the estimates differed by 25% from the measured VO 2. Mean absolute difference increased from 36.7 ml/min in the lowest body mass index group (25 kg/m 2) to 91.7 ml/min in the highest group (40 kg/m 2) (p for trend = 0.001) and was significantly higher in men than in women (65.6 vs 33.9 ml/min, p = 0.001); error was similar by median-split age (p = 0.65) and race (p = 0.34). Similar results were obtained when evaluating each of the other 2 estimating equations. Estimation of VO 2 at rest is inaccurate, especially in men and with increasing adiposity. In conclusion, when clinical hemodynamic assessment is performed, VO 2 should be measured, not estimated.
机译：Fick原理（心输出[Q c] =氧吸收[VO 2] /动静脉差）可用于计算Q C，VO 2经常通过衍生方程估计。为了比较测量与估计的VO 2的准确性，从2研究分析了数据，其中使用道格拉斯袋技术测量静止的VO 2。一项研究包括患有糖尿病的成年人，另一个是对健康成年人的运动研究。静止的VO 2被估计为VO 2（ml / min）= 125ml / min / m 2×体表面积区域（m 2），灵敏度分析评估其他常用方程。平均绝对差异（每分钟毫升）和普通最少产品回归用于评估测量和估计的VO 2之间的协议。总体而言，平均值与估计的VO 2有显着不同（307.2±75.2 vs 259.9±36.7ml / min，P＆ 0.0001），平均绝对差为52.9±43.2ml / min（p <0.0001）; 20％的估计值不同于测量的VO 2. 25％。平均绝对差从最低体重指数组（25kg / m 2）中的36.7ml / min增加到91.7 ml / min最高组（＆ 40 kg / m 2）（p趋势= 0.001），男性显着高于女性（65.6 vs 33.9 ml / min，p = 0.001）;错误是相似的中位数 - 分裂年龄（p = 0.65）和比赛（p = 0.34）。当评估其他2个估计方程中的每一个时获得了类似的结果。静止的VO 2的估计是不准确的，特别是在男性和肥胖的增加。总之，当进行临床血流动力学评估时，应测量VO 2，未估计。

著录项

  • 来源
  • 作者

    NarangN.; GoreM.O.; SnellP.G.; AyersC.R.; LorenzoS.; Carrick-RansonG.; BabbT.G.; LevineB.D.; KheraA.; DeLemosJ.A.; McGuireD.K.;

  • 作者单位

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Donald W. Reynolds Cardiovascular Clinical Research Center Texas Health Presbyterian Hospital;

    Institute of Exercise and Environmental Medicine Texas Health Presbyterian Hospital University of;

    Institute of Exercise and Environmental Medicine Texas Health Presbyterian Hospital University of;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

    Department of Internal Medicine Texas Health Presbyterian Hospital University of Texas;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 心脏、血管（循环系）疾病;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号