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Evidence-based gender findings for children affected by HIV and AIDS - a systematic overview

机译：对受艾滋病毒和艾滋病影响的儿童的循证性别调查结果-系统概述

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This review (under the International Joint Learning Initiative on Children and AIDS) provides a detailed evidence analysis of gender, children and AIDS. Six systematic reviews provide the most up to date evidence base on research surrounding children and HIV on key topics of treatment resistance and adherence, schooling, nutrition, cognitive development and orphaning and bereavement. Traditional systematic review techniques were used to identify all published studies on four key topics, then studies were selected according to adequacy criteria (sufficient size, control group and adequate measures). A gender analysis was performed on included studies, detailing whether gender was measured, results were analysed by gender or any gender-based findings. For family studies, both the gender of the parents and gender of the child are needed. Secondary analysis by gender was performed on existing systematic reviews for treatment resistance and adherence. Of the 12 studies on treatment resistance, 11 did not look at gender. One found boys at a seven-fold risk compared to girls. For medication adherence, gender was not significant. Of the 15 studies on schooling, 12 analysed findings by gender with an overall female disadvantage. Of the 14 studies on nutrition, nine analysed by gender with mixed findings. Of the 54 studies on cognitive development, 17 provided gender data, but only four analysed by gender with few differences established. Of the 15 studies on bereavement, seven analysed data by gender again with mixed findings. Major policies fail to provide gender data for young children. WHO, UNAIDS and the international data sets are not gathered or coded by gender for young children (generally under 15 years of age) despite well-established gender challenges in later life. This review shows that the current evidence base is inadequate. Data on gender variation and outcome are urgently needed to inform policy and research on children and HIV.
机译：这项审查（根据国际儿童与艾滋病联合学习倡议）提供了关于性别，儿童与艾滋病的详细证据分析。六项系统评价提供了围绕儿童和HIV的研究的最新证据，这些研究涉及治疗抗性和依从性，教育，营养，认知发展以及孤儿和丧亲之类的关键主题。使用传统的系统评价技术来识别关于四个关键主题的所有已发表研究，然后根据充分性标准（足够的规模，对照组和足够的措施）选择研究。对纳入的研究进行了性别分析，详细说明了是否测量了性别，是否按性别分析了结果或基于性别的发现。对于家庭学习，既需要父母的性别，也需要孩子的性别。按性别进行的次要分析是针对现有的系统评价治疗耐受性和依从性进行的。在12项关于治疗抗性的研究中，有11项没有考虑性别。一个人发现男孩的风险是女孩的七倍。对于药物依从性，性别不显着。在15项关于入学的研究中，有12项分析了按性别划分的调查结果，这些调查对女性总体不利。在14项营养研究中，有9项按性别进行了分析，结果各异。在54项关于认知发展的研究中，有17项提供了性别数据，但只有4项按性别进行了分析，几乎没有差异。在有关丧亲的15项研究中，有7项再次按性别分析了数据，但发现结果参差不齐。主要政策未能提供幼儿的性别数据。世卫组织，艾滋病规划署和国际数据集并未按性别为幼儿（通常为15岁以下）收集或编码，尽管在以后的生活中存在公认的性别挑战。这项审查表明，目前的证据基础不足。迫切需要有关性别差异和结果的数据，以提供有关儿童和艾滋病毒的政策和研究信息。

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