Molecular epidemiology of HIV type 1 infection in iran: Genomic evidence of CRF35-AD predominance and CRF01-AE infection among individuals associated with injection drug use

JahanbakhshF.; IbeS.; HattoriJ.; MonavariS.H.R.; MatsudaM.; MaejimaM.; IwataniY.; MemarnejadianA.; KeyvaniH.; AzadmaneshK.; SugiuraW.

首页> 外文期刊>AIDS Research and Human Retroviruses >Molecular epidemiology of HIV type 1 infection in iran: Genomic evidence of CRF35-AD predominance and CRF01-AE infection among individuals associated with injection drug use

【24h】

Molecular epidemiology of HIV type 1 infection in iran: Genomic evidence of CRF35-AD predominance and CRF01-AE infection among individuals associated with injection drug use

机译：伊朗HIV 1型感染的分子流行病学：与注射吸毒相关的人群中CRF35-AD优势和CRF01-AE感染的基因组证据

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

To understand the molecular epidemiology of HIV-1 infection in Iran, we conducted the first study to analyze the genome sequence of Iranian HIV-1 isolates. For this cross-sectional study, we enrolled 10 HIV-1-infected individuals associated with injection drug use from Tehran, Shiraz, and Kermanshah. Near full-length genome sequences obtained from their plasma samples were used for phylogenetic tree and similarity plotting analyses. Among 10 isolates, nine were clearly identified as CRF35-AD and the remaining one as CRF01-AE. Interestingly, five of our Iranian CRF35-AD isolates made two clusters with 10 Afghan CRF35-AD isolates in a phylogenetic tree, indicating epidemiological connections among injection drug users in Iran and Afghanistan. In contrast, our CRF01-AE isolate had no genetic relationship with any other CRF01-AE isolates worldwide, even from Afghanistan. This study provides the first genomic evidence of HIV-1 CRF35-AD predominance and CRF01-AE infection among individuals associated with injection drug use in Iran.

机译：为了了解伊朗HIV-1感染的分子流行病学，我们进行了第一项研究，以分析伊朗HIV-1分离株的基因组序列。在这项横断面研究中，我们招募了10位来自德黑兰，设拉子和克曼沙赫的与注射毒品相关的HIV-1感染者。从他们的血浆样品中获得的近乎全长的基因组序列被用于系统发育树和相似性作图分析。在10株分离株中，有9株明确鉴定为CRF35-AD，其余1株鉴定为CRF01-AE。有趣的是，我们的五个伊朗CRF35-AD分离株在系统发育树中与10个阿富汗CRF35-AD分离株形成两个簇，表明伊朗和阿富汗的注射吸毒者之间存在流行病学联系。相反，我们的CRF01-AE分离株与全世界的任何其他CRF01-AE分离株均无遗传关系，即使来自阿富汗也是如此。这项研究提供了在伊朗与注射吸毒相关的人群中HIV-1 CRF35-AD优势和CRF01-AE感染的第一个基因组证据。

著录项

来源
《AIDS Research and Human Retroviruses》 |2013年第1期|共6页
作者
JahanbakhshF.; IbeS.; HattoriJ.; MonavariS.H.R.; MatsudaM.; MaejimaM.; IwataniY.; MemarnejadianA.; KeyvaniH.; AzadmaneshK.; SugiuraW.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Clinical standard; Outcome; Peritoneal dialysis; Quality;

机译：临床标准;结果;腹膜透析;质量;

相似文献

外文文献
中文文献
专利

1. Molecular epidemiology of HIV type 1 infection in iran: Genomic evidence of CRF35-AD predominance and CRF01-AE infection among individuals associated with injection drug use [J] . JahanbakhshF., IbeS., HattoriJ., AIDS Research and Human Retroviruses . 2013,第1期

机译：伊朗HIV 1型感染的分子流行病学：与注射吸毒相关的人群中CRF35-AD优势和CRF01-AE感染的基因组证据
2. Molecular epidemiology of HIV-1 infection and full-length genomic analysis of circulating recombinant form 07_BC strains from injection drug users in Taiwan. [J] . Lin YT, Lan YC, Chen YJ, The Journal of Infectious Diseases . 2007,第9期

机译：HIV-1感染的分子流行病学和台湾注射吸毒者的循环重组07_BC株的全长基因组分析。
3. Molecular Epidemiology of HIV-1 Infection and Full-Length Genomic Analysis of Circulating Recombinant Form 07_BC Strains from Injection Drug Users in Taiwan [J] . Yu-Ting Lin12a Yu-Ching Lan17a Yen-Ju Chen12 Yu-Hui Huang12 Cheng-Ming Lee1 Tze-Tze Liu3 Wing-Wai Wong5 Jyh-Yuan Yang6 Chin-Tien Wang24 and Yi-Ming Arthur Chen12 Journal of Infectious Diseases . 2007,第9期

机译：台湾注射吸毒者HIV-1感染的分子流行病学及循环重组07_BC株的全长基因组分析
4. Molecular epidemiology of influenza A infections in swine at agricultural fairs [C] . Andrew S. Bowman, Karla M. Stucker, Seth Schobel, Annual^Meeting of the American Association^of^Swine^Veterinarians. . 2014

机译：流感流感流感流感流动博览会农业展览会感染
5. Molecular epidemiology and transmission dynamics of HCV infection in injection drug users in southern China. [D] . Tan, Yi. 2008

机译：中国南方注射吸毒者中HCV感染的分子流行病学和传播动力学。
6. Short Communication: Molecular Epidemiology of HIV Type 1 Infection in Northern Greece (2009–2010): Evidence of a Transmission Cluster of HIV Type 1 Subtype A1 Drug-Resistant Strains Among Men Who Have Sex with Men [O] . Zoi-Anna Antoniadou, Ioanna Kousiappa, Lemonia Skoura, -1

机译：简短交流：希腊北部HIV 1型感染的分子流行病学研究（2009年至2010年）：与男性发生性行为的HIV 1型亚型A1亚型耐药菌株传播群的证据
7. Short Communication: Molecular Epidemiology of HIV Type 1 Infection in Northern Greece (2009–2010): Evidence of a Transmission Cluster of HIV Type 1 Subtype A1 Drug-Resistant Strains Among Men Who Have Sex with Men [O] . Zoi-Anna Antoniadou, Ioanna Kousiappa, Lemonia Skoura, 2014

机译：短期通信：希腊北部HIV 1型感染的分子流行病学（2009-2010）：与男性发生性发生性关系的男性患者患者患者1型亚型A1耐药菌株的证据
8. HIV Infection and Risk, Prevention, and Testing Behaviors Among Persons Who Inject Drugs: National HIV Behavioral Surveillance Injection Drug Use, 20 U.S. Cities, 2012. HIV Surveillance Report Special Report, Number 11. [R] . Wade, I., Wejnert, C., Cooley, L., 2015

机译：注射毒品者的艾滋病毒感染和风险，预防和检测行为：全国艾滋病毒行为监测注射吸毒，美国20个城市，2012年。艾滋病毒监测报告特别报告，第11号。

Molecular epidemiology of HIV type 1 infection in iran: Genomic evidence of CRF35-AD predominance and CRF01-AE infection among individuals associated with injection drug use

摘要

著录项

相似文献

相关主题

期刊订阅