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首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >Occlusion time for Amplatzer vascular plug in the management of pulmonary arteriovenous malformations.
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Occlusion time for Amplatzer vascular plug in the management of pulmonary arteriovenous malformations.

机译：Amplatzer血管栓塞的阻塞时间可用于治疗肺动静脉畸形。

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OBJECTIVE: The occlusion time, that is, the interval between device deployment and complete occlusion of the vessel, associated with the use of embolic devices influences the risk of embolic complications caused by small clots that can form over the surface of a device and break away. The purpose of our study was to determine the time for an Amplatzer vascular plug to bring about percutaneous transcatheter occlusion of a pulmonary arteriovenous malformation (PAVM). MATERIALS AND METHODS: We retrospectively studied the occlusion times of Amplatzer vascular plugs in the management of 12 PAVMs. We recorded the number, location, type (simple or complex), and diameter and number of feeding arteries of PAVMs; the number and size of devices needed to occlude each PAVM; and the occlusion time for each PAVM. The occlusion time is the time interval from device placement to complete occlusion of the PAVM. Occlusion time was determined by recording the time between acquisition of the first angiographic image after deployment of the device and the angiogram that showed total occlusion of the PAVM. The relevant literature on the subject was reviewed. RESULTS: All PAVMs managed were supplied by a single feeding artery. The average diameter of the feeding arteries was 4.8 mm (range, 3.0-11.2 mm). All PAVMs were occluded by deployment of a single Amplatzer vascular plug. Vascular plug sizes ranged from 4 to 16 mm. The mean occlusion time was 3 minutes 20 seconds (range, 1 minute 49 seconds-5 minutes 16 seconds). There were no immediate complications, including air embolism and thromboembolism. CONCLUSION: The occlusion time determined in our study and the need to place only one Amplatzer vascular plug in each feeding artery to achieve complete occlusion in most cases suggest that the device is safe for management of PAVM with no increased risk of systemic embolization. The use of the Amplatzer vascular plug for PAVM embolization is a relatively recent development. Long-term follow-up studies are needed to assess recanalization rates, radiation exposure rates, and risk of device migration.
机译：目的：闭塞时间，即器械展开和完全闭塞血管之间的间隔，与栓塞器械的使用有关，会影响由可能在器械表面形成并脱落的小凝块引起的栓塞并发症的风险。我们研究的目的是确定Amplatzer血管栓塞引起经皮经导管阻塞肺动静脉畸形（PAVM）的时间。材料与方法：我们回顾性研究了在管理12台PAVM时Amplatzer血管栓塞的阻塞时间。我们记录了PAVMs的数量，位置，类型（简单或复杂），进食动脉的直径和数量;阻塞每个PAVM所需的设备数量和大小;以及每个PAVM的遮挡时间。阻塞时间是从设备放置到PAVM完全阻塞的时间间隔。通过记录在装置部署后获取第一张血管造影图像与显示PAVM完全阻塞的血管造影图之间的时间来确定阻塞时间。审查了有关该主题的相关文献。结果：所有管理的PAVM均由一条进食动脉提供。喂养动脉的平均直径为4.8毫米（范围3.0-11.2毫米）。通过部署单个Amplatzer血管塞来阻塞所有PAVM。血管塞尺寸为4至16 mm。平均阻塞时间为3分钟20秒（范围1分钟49秒-5分钟16秒）。没有立即发生的并发症，包括空气栓塞和血栓栓塞。结论：在我们的研究中确定的闭塞时间以及在大多数情况下在每个进食动脉中仅需放置一个Amplatzer血管塞以实现完全闭塞的必要性表明，该装置可安全管理PAVM，而不会增加全身栓塞的风险。将Amplatzer血管塞用于PAVM栓塞是一个相对较新的发展。需要进行长期随访研究，以评估再通率，放射线暴露率和设备迁移的风险。

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