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Vesselplasty: a new technical approach to treat symptomatic vertebral compression fractures.

机译:血管成形术:一种治疗症状性椎体压缩性骨折的新技术方法。

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OBJECTIVE: The objective of our study was to evaluate the effectiveness and safety of vesselplasty to treat symptomatic vertebral compression fractures (VCFs). SUBJECTS AND METHODS: Twenty-nine patients undergoing vesselplasty at our institution between April 2006 and February 2008 were enrolled in the study. All patients had been undergoing medical therapy for one or more painful VCFs. Pain, mobility, and analgesic use scores were obtained, and restoration of vertebral body height was evaluated. A two-tailed paired Student's t test was used to compare differences in the mean scores for levels of pain, mobility, and analgesic use before and after the procedure and to evaluate changes in vertebral body height. We analyzed the influence of the age of the fracture and its cause in the variations in the pain, mobility, and analgesic use scores. RESULTS: Seven of the 29 patients had fractures in more than one level, for a total of 37 procedures. The cause of the vertebral collapse was osteoporosis in 27 (73%), high-impact trauma in five (13.5%), myeloma in three (8%), and metastatic fracture in two (5.4%). The average pain score before treatment was 8.72 +/- 1.25 (SD), whereas the average pain score after treatment was 3.38 +/- 2.35. The average mobility score before treatment was 2.31 +/- 1.94, whereas the average mobility score after treatment was 0.59 +/- 1.05 (p < 0.001). The average analgesic use score before treatment was 3.07 +/- 1.46, whereas it was 1.86 +/- 1.90 after treatment (p < 0.001). There was no evidence of clinical complications. CONCLUSION: Vesselplasty offers statistically significant benefits in improvements of pain, mobility, and the need for analgesia in patients with symptomatic VCFs, thus providing a safe alternative in the treatment of these fractures.
机译:目的:本研究的目的是评估血管成形术治疗有症状的椎体压缩性骨折(VCF)的有效性和安全性。研究对象和方法:2006年4月至2008年2月间在我们机构进行血管成形术的29例患者入选了该研究。所有患者均已接受一种或多种疼痛性VCF的药物治疗。获得疼痛,活动性和止痛剂使用评分,并评估椎体高度的恢复。两尾配对的学生t检验用于比较手术前后疼痛,活动性和止痛药使用的平均评分差异,并评估椎体高度的变化。我们分析了骨折年龄及其原因对疼痛,活动性和止痛药使用评分变化的影响。结果:29例患者中有7例骨折水平超过一个级别,总共进行了37例手术。椎体塌陷的原因是:骨质疏松症27例(73%),高冲击性创伤5例(13.5%),骨髓瘤3例(8%)和转移性骨折2例(5.4%)。治疗前的平均疼痛评分为8.72 +/- 1.25(SD),而治疗后的平均疼痛评分为3.38 +/- 2.35。治疗前的平均迁移率得分为2.31 +/- 1.94,而治疗后的平均迁移率得分为0.59 +/- 1.05(p <0.001)。治疗前的平均镇痛剂使用评分为3.07 +/- 1.46,而治疗后为1.86 +/- 1.90(p <0.001)。没有临床并发症的证据。结论:在有症状的VCF患者中,血管成形术在改善疼痛,活动性和镇痛方面具有统计学上的显着优势,从而为这些骨折的治疗提供了一种安全的选择。

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