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首页> 外文期刊>Drug discovery today >Overcoming psychological barriers to good discovery decisions.
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Overcoming psychological barriers to good discovery decisions.

机译:克服了良好的发现决策的心理障碍。

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摘要

Better individual and team decision-making should enhance R&D performance. Reproducible biases affecting human decision-making, known as cognitive biases, are well understood by psychologists. These threaten objectivity and balance and so are credible causes for continuing unpleasant surprises in Development and high operating costs. For four of the most common and insidious cognitive biases, we consider the risks to R&D decision-making and contrast current practice with use of evidence-based medicine by healthcare practitioners. Feedback on problem-solving performance in simulated environments could be one of the simplest ways to help teams improve their selection of compounds and effective screening sequences. Computational tools that encourage objective consideration of all of the available information might also contribute.
机译:更好的个人和团队决策应提高研发性能。 心理学家,影响人为决策的可重复性偏见,称为认知偏见。 这些威胁的客观性和平衡,因此可靠的原因在发展和高运营成本中继续令人不快的惊喜。 对于其中四个最常见和阴险的认知偏见,我们认为R&D决策和对比当前实践的风险与医疗保健从业者使用循证医学。 关于模拟环境中解决问题的反馈可能是帮助团队改善它们选择化合物和有效筛查序列的最简单方法之一。 鼓励客观考虑所有可用信息的计算工具也可能有贡献。

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