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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >3D bioprinting and its in vivo applications
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3D bioprinting and its in vivo applications

机译：3D BioPlinting及其体内应用

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摘要

The purpose of 3D bioprinting technology is to design and create functional 3D tissues or organs in situ for in vivo applications. 3D cell-printing, or additive biomanufacturing, allows the selection of biomaterials and cells (bioink), and the fabrication of cell-laden structures in high resolution. 3D cell-printed structures have also been used for applications such as research models, drug delivery and discovery, and toxicology. Recently, numerous attempts have been made to fabricate tissues and organs by using various 3D printing techniques. However, challenges such as vascularization are yet to be solved. This article reviews the most commonly used 3D cell-printing techniques with their advantages and drawbacks. Furthermore, up-to-date achievements of 3D bioprinting in in vivo applications are introduced, and prospects for the future of 3D cell-printing technology are discussed. (c) 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 444-459, 2018.
机译：3D BioPlinting技术的目的是在体内应用设计和创建功能3D组织或器官。 3D细胞印刷或添加性生物制造允许选择生物材料和细胞（生物链），并以高分辨率制造细胞升起的结构。 3D细胞印刷结构也已用于研究模型，药物递送和发现等应用，以及毒理学。 最近，已经通过使用各种3D打印技术来制造组织和器官的许多尝试。 然而，尚未解决血管化等挑战。 本文审查了最常用的3D细胞印刷技术，具有它们的优点和缺点。 此外，介绍了在体内应用中的3D生物印刷内的最新成果，并讨论了3D细胞印刷技术的未来的前景。 （c）2017年Wiley期刊，Inc。J生物保解员B：苹果生物摩特，106B：444-459,2018。

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