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Mechanical Loading of the Femoral Neck in Human Locomotion

机译:人类运动股骨颈部机械负荷

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ABSTRACT Advancing age and reduced loading are associated with a reduction in bone formation. Conversely, loading increases periosteal apposition and may reduce remodeling imbalance and slow age‐related bone loss, an important outcome for the proximal femur, which is a common site of fracture. The ability to take advantage of bone's adaptive response to increase bone strength has been hampered by a lack of knowledge of which exercises and specific leg muscles load the superior femoral neck: a common region of microcrack initiation and progression following a sideways fall. We used an in vivo method of quantifying focal strains within the femoral neck in postmenopausal women during walking, stair ambulation, and jumping. Relative to walking, stair ambulation and jumping induced significantly higher strains in the anterior and superior aspects of the femoral neck, common regions of microcrack initiation and progression following a fall. The gluteus maximus, a hip extensor muscle, induced strains in the femoral neck during stair ambulation and jumping, in contrast to walking which induced strains via the iliopsoas, a hip flexor. The ground reaction force was closely associated with the level of strain during each task, providing a surrogate indicator of the potential for a given exercise to load the femoral neck. The gluteal muscles combined with an increased ground reaction force relative to walking induce high focal strains within the anterosuperior region of the femoral neck and therefore provide a target for exercise regimens designed to slow bone loss and maintain or improve microstructural strength. Model files used for calculating femoral neck strains are available at uitbl.mechse.illinois.edu/downloads ? 2018 American Society for Bone and Mineral Research.
机译:摘要推进年龄和减少的载荷与骨形成的减少有关。相反,加载增加骨骼联系,并可减少重塑不平衡和缓慢的年龄相关的骨质损失,这是近端股骨的重要结果,这是骨折的常见部位。利用骨骼适应性响应来增加骨骼强度的能力被缺乏了解,缺乏了解哪种练习和特定的腿部肌肉负担较好的股骨颈:在侧面落下后的微裂纹启动和进展的公共区域。我们在步行,楼梯散步和跳跃期间使用了在绝经后妇女的股骨颈内量化局灶性菌株的体内方法。相对于行走,阶梯的气动和跳跃诱导股骨颈前和较高方面的显着更高的菌株,秋季后的微裂纹引发和进展的常见区域。臀部伸肌肌肉,髋部伸肌肌肉,股骨颈颈部诱导菌株,与髂腰部诱导菌株的行走相反,伴随着髋部屈曲。接地反作用力与每个任务期间的应变水平密切相关,提供给定运动的潜在潜力的替代指示剂,以装载股骨颈。臀部肌肉相对于行走的增加的地面反作用力诱导高焦点诱导股骨颈部的高焦点,因此为锻炼方案提供了设计成减缓骨质损失和维持或提高微观结构强度的靶标。用于计算股骨颈部菌株的模型文件可在Uitbl.mechse.illinoIs.edu/downloads上获得? 2018年美国骨骼和矿物学研究。

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