首页> 外文期刊>Journal of Camel Practice and Research >CAMEL MILK EFFICIENCY IN PROTECTING RAT TESTES AGAINST LEAD ACETATE TOXICITY
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CAMEL MILK EFFICIENCY IN PROTECTING RAT TESTES AGAINST LEAD ACETATE TOXICITY

机译:骆驼牛奶效率保护大鼠患有铅醋酸铅毒性

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摘要

Two experiments were conduted to evaluate the role of camel milk in preventing the detrimental effect of lead on rat. In the first, 6 groups of adult male rats were administered daily for 60 days the following : group 1 saline; group 2 camel milk; group 3 cow milk, group 4 lead acetate; group 5 camel milk plus lead and group 6 cow milk plus lead. In the second, pregnant female rats were divided and treated following the first experiment. The female were allowed to deliver pups, the treatment continued until weaning of the pups then, the male pups were left without treatment until puberty. Lead caused significant reduction in the body and reproductive organ weights; plasma and testicular testosterone, testicular zinc; antioxidant enzymes, luteinising and follicle stimulating hormones and semen characteristics, while it caused significant increase in malondialdehyde; testicular cholesterol and testicular and plasma lead. Camel milk treatment improved the estimated parameters in adult male rat. However, it could not alleviate these parameters in male rats born for mothers exposed to lead during pregnancy and lactation periods. Camel milk treatment improved the evaluated parameters in adult male rats exposed to lead intoxication albeit not all were identical to the control levels, however, it could not improve these parameters in adult male rats born for mothers exposed to lead during pregnancy and lactation.
机译:调查了两个实验,以评估骆驼牛奶在预防铅对大鼠的不利影响的作用。首先,每日施用6组成年雄性大鼠60天:第1组盐水;第2组骆驼牛奶;第3组牛奶,第4组醋酸铅;第5组骆驼牛奶加铅和第6组牛奶加铅。在第二,在第一次实验后分开和处理孕妇大鼠。女性被允许递送幼崽,治疗持续直至幼崽断奶,雄性幼崽在没有治疗的情况下留下直到青春期。铅导致体内和生殖器官重量显着降低;血浆和睾丸睾酮,睾丸锌;抗氧化酶,刻度化和卵泡刺激激素和精液特征,同时它引起了丙二醛的显着增加;睾丸胆固醇和睾丸和血浆铅。骆驼牛奶处理改善了成年雄性大鼠的估计参数。然而,它不能缓解在孕妇出生于母亲的男性大鼠中的这些参数,在怀孕和哺乳期间暴露于铅。骆驼牛奶治疗改善了暴露于铅中的成年雄性大鼠的评估参数尽管并非所有与对照水平相同,但是它不能改善为妊娠和哺乳期间暴露于铅的成年男性大鼠中的这些参数。

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