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首页> 外文期刊>Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism >Collateral perfusion using arterial spin labeling in symptomatic versus asymptomatic middle cerebral artery stenosis
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Collateral perfusion using arterial spin labeling in symptomatic versus asymptomatic middle cerebral artery stenosis

机译：使用动脉旋转标记在症状与无症状中间脑动脉狭窄的抵押品灌注

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摘要

The purpose was to assess the difference of collaterals in symptomatic versus asymptomatic patients with unilateral middle cerebral artery (MCA) stenosis by comparing cerebral blood flow (CBF) at two post labeling delays (PLD) using three-dimensional pseudo-continuous arterial spin labeling (3D pCASL). Eighty-one patients (49 symptomatic and 32 asymptomatic) with unilateral MCA stenosis = 50% who underwent pCASL with two PLDs were included. Mean CBF and CBF subtraction images between two PLDs of MCA territories were compared in symptomatic and asymptomatic groups, respectively. Compared with the asymptomatic group, patients with symptomatic MCA stenosis had significantly lower CBF in the MCA territory of stenotic side at each PLD. The CBF of stenotic territory showed greater increase than that of normal side from PLD 1.5 to 2.5 s. The CBF of asymptomatic MCA territory increased similarly with that of symptomatic MCA territory from PLD of 1.5 to 2.5 s in stenotic side, while symptomatic patients experienced significantly slower antegrade flow. On CBF subtraction images, asymptomatic patients showed larger volume of differences between PLD of 1.5 and 2.5 s compared with those of symptomatic patients (p = 0.037). The results suggest that more robust collateral perfusion on two-delay 3D pCASL is present in asymptomatic patients compared with symptomatic patients.
机译：目的是通过使用三维伪连续动脉旋转标记（ 3D pcasl）。八十一位患者（49例症状和32例无症状），单侧MCA狭窄＆ = 50％接受了两层PLD的PCASL。在症状和无症状的群体中分别比较了两种MCA领土之间的平均CBF和CBF减法图像。与无症状组相比，患有症状MCA狭窄的患者在每个PLD的狭窄方面的MCA境内显着降低了CBF。狭窄地区的CBF比PLD 1.5至2.5秒的正常方面的增加表现出更大的增加。无症状MCA领土的CBF与狭窄的PLD的症状MCA领土的CBF同样地增加，而症状患者的症状患者的令人显着越慢。在CBF减法图像上，与症状患者的患者相比，无症状患者在1.5和2.5秒之间显示出更大的差异（P = 0.037）。结果表明，与症状患者相比，无症状患者中存在两延迟3D PCAS1上的更强大的抵押灌注。

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