...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Can point shear wave elastography differentiate focal nodular hyperplasia from hepatocellular adenoma
【24h】

Can point shear wave elastography differentiate focal nodular hyperplasia from hepatocellular adenoma

机译：Can Point Shear波形弹性摄影区分肝细胞腺瘤的局灶性结节性增生

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract Purpose Focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) are liver tumors that require different management. We assessed the potential of point shear wave elastography (pSWE) to differentiate FNH from HCA and the interobserver and intraobserver reliability of pSWE in the examination of these lesions and of native liver tissue (NLT). Methods The study included 88 patients (65 FNH, 23 HCA). pSWE was performed by two experienced liver sonographers (observers 1 [O1] and 2 [O2]) and acquired within the lesion of interest and NLT. Group differences, optimal cutoff for characterization and interobserver reliability was assessed with Mann‐Whitney‐U, area under the ROC curce (AUROC) and intraclass correlation coefficient (ICC). Intraobserver reliability in NLT was assessed in 20 healthy subjects using ICC. Results Median stiffness was significantly higher in FNH than in HCA (7.01 kPa vs 4.98 kPa for O1 ( P ?=?0.017) and 7.68 kPa vs 6.00 kPa for O2 ( P ?=?0.031)). A cutoff point for differentiation between the two entities could not be determined with an AUROC of 0.67 (O1) and 0.69 (O2). Interobserver reliability was good for lesion‐ stiffness (ICC?=?0.86) and poor for NLT stiffness (ICC?=?0.09). In healthy subjects, intraobserver reliability for NLT‐stiffness was poor for O1 (ICC?=?0.23) and moderate for O2 (ICC?=?0.62). Conclusion This study shows that pSWE cannot reliably differentiate FNH from HCA. Interobserver and intraobserver reliability for pSWE in NLT were insufficient. Interpretation of results gained with this method should be done with great caution.
机译：摘要目的局灶性结节性增生（FNH）和肝细胞腺瘤（HCA）是需要不同管理的肝肿瘤。我们评估了点剪力波形弹性造影（PSWE）的潜力，以区分HCA和Interobserver和Pswe的intraobserver可靠性在检查这些病变和天然肝组织（NLT）中。方法该研究包括88名患者（65英尺，23 HCA）。 PSWE由两个经验丰富的肝脏超声波（观察者1 [o1]和2 [O2]）进行，并在兴趣的病变和NLT内获得。组差异，用于表征和Interobserver可靠性的最佳截止，在Roc Curce（Auroc）下的曼诺·惠特（Auroc）和腹部相关系数（ICC）中评估了曼诺 - 惠特尼 - U区。使用ICC的20个健康受试者评估NLT中的Intraobserver可靠性。结果FNH中的中值刚度显着高于HCA（7.01kPa Vs 4.98 KPa，O1（p？= 0.017）和7.68kPa与O2的6.00kPa（p？= 0.031））。不能用0.67（O1）和0.69（O2）的Auroc确定两个实体之间分化的截止点。 Interobserver可靠性适用于病变刚度（ICC？= 0.86）和NLT刚度的差（ICC？=？0.09）。在健康的主题中，O1（ICC？= 0.23）和O2（ICC？= 0.62）中等的NLT - 刚度的血管内的可靠性差（ICC？= 0.62）。结论本研究表明，PSWE不能从HCA可靠地区分FNH。 NLT中PSWE的Interobserver和intraObserver可靠性不足。应当非常谨慎地进行这种方法获得的结果。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号