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Anti-GQ1b Spectrum Disorders

机译:抗GQ1B谱紊乱

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摘要

Dear Sir, It is time we acknowledge and teach that anti-GQ1b antibodies belong to a spectrum disorder rather than being specific for a specific syndrome. Anti-GQ1b antibodies have been associated with the Miller Fisher syndrome as early as 1950, but the incidence of the Miller Fisher syndrome is less than 1 in a million, while the antibodies are being detected in several other disorders, including the Guillain-Barre syndrome, Bick-erstaffs brainstem encephalitis, pharyngeal-cervical-brachial weakness, acute oph-thalmoplegia without ataxia, oph-thalmoplegia secondary to one extraocular nerve pathology,ophthalmoplegia with bilateral extraocular mononeuropathies, external ophthalmoplegia with areflexia, ophthalmoplegia with normal deep tendon reflexes, or external and internal ophthalmoplegia (pupillary dysfunction).
机译:亲爱的先生,是时候我们承认并教导抗GQ1B抗体属于谱系障碍,而不是特异性综合征。 早在1950年,抗GQ1B抗体已与米勒Fisher综合征有关,但米勒Fisher综合征的发病率小于1百万,而在其他几种疾病中检测到抗体,包括Guillain-Barre综合征 ,Bick-eRstafs脑干脑炎,咽部 - 宫颈胸肌炎,急性OPH-thaloplegia没有共济失调,OPH-thaloplegia继发于一个非外表神经病理学,眼科凝视与双侧外插疗法,外部眼科动脉粥样硬脑膜术,眼镜术,眼科凝血症患有正常的肌腱反射,或 外部和内部眼镜术(瞳孔功能障碍)。

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