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首页> 外文期刊>Journal of drug targeting >Multifunctional hybrid-carbon nanotubes: new horizon in drug delivery and targeting
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Multifunctional hybrid-carbon nanotubes: new horizon in drug delivery and targeting

机译：多功能杂交碳纳米管：药物递送和靶向的新地平线

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摘要

Carbon nanotubes (CNTs) have emerged as an intriguing nanotechnological tool for numerous biomedical applications including biocompatible modules for the bioactives delivery ascribed to their unique properties, such as greater loading efficiency, biocompatibility, non-immunogenicity, high surface area and photoluminescence, that make them ideal candidate in pharmaceutical and biomedical science. The design of multifunctional hybrid-CNTs for drug delivery and targeting may differ from the conventional drug delivery system. The conventional nanocarriers have few limitations, such as inappropriate availability of surface-chemical functional groups for conjugation, low entrapment/loading efficiency as well as stability as per ICH guidelines with generally regarded as safe (GRAS) prominences. The multifunctional hybrid-CNTs will sparked and open a new door for researchers, scientist of the pharmaceutical and biomedical arena. This review summarizes the vivid aspects of CNTs like characterization, supramolecular chemistry of CNTs-dendrimer, CNTs-nanoparticles, CNTs-quantum dots conjugate for delivery of bioactives, not discussed so far.
机译：碳纳米管（CNT）作为许多生物医学应用的碳纳米管（CNT）被出现为具有生物相容性模块的许多生物医学应用，该应用用于赋予其独特性质的生物相容性，例如更大的负载效率，生物相容性，非免疫原性，高表面积和光致发光，使其成为制造它们制药和生物医学科学的理想候选人。用于药物递送和靶向的多官能杂种CNT的设计可能与常规药物递送系统不同。常规纳米载体具有很少的限制，例如表面化学官能团的不适当的可用性，用于缀合，滞留/装载效率低以及通常被认为是安全（GRAS）突出的ICH指南的稳定性。多功能的混合CNT将引发和开辟一门用于研究人员，制药和生物医学舞台的科学家。本综述总结了CNTs表征的生动方面，CNTs-Dendrimer，CNTs-Nanoparticly，CNTS-量子点缀合物的CNTS-纳米粒子，用于递送生物术，未讨论。

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