Advances in in-situ product recovery (ISPR) in whole cell biotechnology during the last decade

Van Hecke Wouter; Kaur Guneet; De Wever Heleen

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Advances in in-situ product recovery (ISPR) in whole cell biotechnology during the last decade

机译：近十年来全细胞生物技术中原位产物回收（ISPR）的进展

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The review presents the state-of-the-art in the applications of in-situ product recovery (ISPR) in whole-cell biotechnology over the last 10 years. It summarizes various ISPR-integrated fermentation processes for the production of a wide spectrum of bio-based products. A critical assessment of the performance of various ISPR concepts with respect to the degree of product enrichment, improved productivity, reduced process flows and increased yields is provided. Requirements to allow a successful industrial implementation of ISPR are also discussed. Finally, supporting technologies such as online monitoring, mathematical modeling and use of recombinant microorganisms with ISPR are presented

机译：该综述介绍了过去十年来原位产品回收（ISPR）在全细胞生物技术中的最新应用。它总结了用于生产多种生物基产品的各种ISPR集成发酵工艺。提供了关于各种ISPR概念在产品富集程度，提高的生产率，减少的工艺流程和增加的产量方面的性能的重要评估。还讨论了成功实施ISPR的要求。最后，介绍了支持技术，例如在线监测，数学建模以及使用ISPR的重组微生物

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《Biotechnology Advances: An International Review Journal》 |2014年第7期|共11页
作者
Van Hecke Wouter; Kaur Guneet; De Wever Heleen;
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正文语种 eng
中图分类生物工程学（生物技术）;
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1. Advances in in-situ product recovery (ISPR) in whole cell biotechnology during the last decade [J] . Van Hecke Wouter, Kaur Guneet, De Wever Heleen Biotechnology Advances: An International Review Journal . 2014,第7期

机译：近十年来全细胞生物技术中原位产物回收（ISPR）的进展
2. Microbial Production of Propionic Acid with Propionibacterium freudenreichii Using an Anion Exchanger-Based In Situ Product Recovery (ISPR) Process with Direct and Indirect Contact of Cells [J] . Peng Wang, Yunshan Wang, Zhiguo Su Applied Biochemistry and Biotechnology . 2012,第4期

机译：使用直接和间接接触细胞的基于阴离子交换剂的原位产物回收（ISPR）工艺，利用费氏丙酸杆菌微生物生产丙酸
3. Microbial production of propionic acid with Propionibacterium freudenreichii using an anion exchanger-based in situ product recovery (ISPR) process with direct and indirect contact of cells [J] . Wang P., Wang Y., Su Z. Applied biochemistry and biotechnology, Part A. enzyme engineering and biotechnology . 2012,第4期

机译：使用直接和间接接触细胞的基于阴离子交换剂的原位产物回收（ISPR）工艺，利用费氏丙酸杆菌微生物生产丙酸
4. In-situ product removal (ISPR) of functional proteins from prokaryotic cultivations by high specific magnetic separation [C] . A Scholz, M. Cerff, C. Posten American Filtration and Separations Society annual conference . 2012

机译：通过高比磁分离从原核生物中去除功能蛋白的原位产物（ISPR）
5. Development of new tools for the application of biotechnology to agricultural improvement and assessing risks of biotechnology and its products [D] . Cook, Meridith Ayn 2008

机译：开发将生物技术应用于农业改良和评估生物技术及其产品风险的新工具
6. Enhanced production of styrene by engineered Escherichia coli and in situ product recovery (ISPR) with an organic solvent [O] . Kyungsoo Lee, Hyun Bae Bang, Yoon Hyeok Lee, 2013

机译：通过工程化的大肠杆菌提高苯乙烯的生产水平，并使用有机溶剂进行原位产物回收（ISPR）
7. Future directions for in-situ product removal (ISPR) [O] . Woodley John, Bisschops Marc, Straathof Adrie J J, 2008

机译：现场产品清除的未来方向（IspR）

Advances in in-situ product recovery (ISPR) in whole cell biotechnology during the last decade

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