• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of glaucoma >Intravenous Hypertonic Saline to Lower Intraocular Pressure in Ocular Hypertension and Primary Open-angle and Exfoliation Glaucoma
【24h】

Intravenous Hypertonic Saline to Lower Intraocular Pressure in Ocular Hypertension and Primary Open-angle and Exfoliation Glaucoma

机译：静脉注射高渗盐水至较低眼压眼压的眼压和初级开口角和剥离青光眼

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose:The purpose of this article was to quantitate the effect of intravenous hypertonic saline (IVHTS) on elevated intraocular pressure (IOP) among 3 groups of glaucoma patients or suspects.Materials and Methods:Among the forty-four patients with IOP 24 to 30mmHg included in this study, 13 had ocular hypertension (OHT), 14 primary open-angle glaucoma (POAG), and 17 exfoliation glaucoma (ExG). Participants received a bolus of 23.4% IVHTS (1.0mmol/kg) through an antecubital vein. We measured IOP, heart rate, and blood pressure before the bolus, thereafter every minute for 10 minutes, and less frequently for 2 hours.Results:The median baseline IOP was 24mmHg (range, 24 to 30mmHg), 26.5mmHg (range, 24 to 30mmHg), and 26mmHg (range, 24 to 30mmHg) in OHT, POAG, and ExG patients, respectively. Sixteen minutes after the bolus, IOP was a median of 9mmHg (range, 4 to 12mmHg), 10mmHg (range, 6 to 12mmHg), and 10mmHg (range, 4 to 14mmHg) lower in OHT, POAG, and ExG groups (P=0.70), respectively. After 1 hour, the median IOP reduction was similar between ExG (9mmHg; range, 4 to 14mmHg) and POAG patients (9.5mmHg; range, 6 to 12mmHg) but lower in OHT patients (6mmHg; range, 2 to 9mmHg; P=0.006). Heart rate decreased by a median of 7 beats/min. Blood pressure increased within 3 minutes (median, mmHg; 15 systolic; 5 diastolic), but returned to baseline at 10 minutes. Within 1 to 3 minutes of treatment, 36 (82%) patients felt pain in the infusion arm, and 29 (66%) reported a feeling of warmth in their head.Conclusions:IVHTS reduced IOP effectively in all groups.
机译：目的：本文的目的是定量静脉高渗盐水（IVHTS）对3组青光眼患者或怀疑的静脉内压（IOP）的影响。材料和方法：44例IOP 24至30mmHg中的患者本研究包括在本研究中，13个具有眼高血压（OHT），14个初级开口荧光眼（POAG）和17个剥离青光眼（EXG）。参与者通过抗腊肠静脉收到23.4％IVHTS（1.0mmol / kg）的推注。在推注之前测量IOP，心率和血压，此后每分钟10分钟，较少频率为2小时。结果：中位数基线IOP为24mmHg（范围，24至30mmHg），26.5mmHg（范围，24 30mmHg）和26mmHg（范围，24至30mmHg）分别在OHT，POAG和EXG患者中。推注后十六分钟，IOP是9mmHg（范围，4至12mMHg）的中位数，10mMHg（范围，6至12mMHg），10mmHg（范围为4至14mmHg），低于OHT，POAG和EXG组（P = 0.70）分别。 1小时后，中位数IOP减少在exg（9mmHg;范围，4至14mmHg）和POG患者（范围，6至12mmHg）之间相似，但在OHT患者（6mmHg;范围，2至9mmHg; P = 0.006）。心率通过7次/分钟的中位数下降。血压在3分钟内增加（中位数，mmHg; 15个收缩; 5个舒张性），但在10分钟后返回基线。在1至3分钟内治疗后，36例（82％）患者在输注臂上毛毡疼痛，29例（66％）报告了他们的头部温暖的感觉。结论：IVHTS在所有群体中有效减少IOP。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号