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The American Heart Association Scientific Statement on salt sensitivity of blood pressure: Prompting consideration of alternative conceptual frameworks for the pathogenesis of salt sensitivity?

机译:美国心脏协会对血压盐敏感性的科学陈述:促使对盐敏感性发病机制的替代概念框架的促进思考?

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摘要

Recently, the American Heart Association (AHA) published a scientific statement on salt sensitivity of blood pressure which emphasized a decades old conceptual framework for the pathogenesis of this common disorder. Here we examine the extent to which the conceptual framework for salt sensitivity emphasized in the AHA Statement accommodates contemporary findings and views of the broader scientific community on the pathogenesis of salt sensitivity. In addition, we highlight alternative conceptual frameworks and important contemporary theories of salt sensitivity that are little discussed in the AHA Statement. We suggest that greater consideration of conceptual frameworks and theories for salt sensitivity beyond those emphasized in the AHA Statement may help to advance understanding of the pathogenesis of salt-induced increases in blood pressure and, in consequence, may lead to improved approaches to preventing and treating this common disorder.
机译:最近,美国心脏协会(AHA)发表了一份关于血压盐敏感性的科学陈述,这些血压强调了这几十年来这种常见疾病的发病机制的概念框架。 在这里,我们研究了AHA声明中强调的盐敏感度概念框架的程度,适应更广泛的科学界对盐敏感性发病机制的当代调查结果和观点。 此外,我们突出了替代概念框架和重要的当代盐敏感理论,这在AHA声明中很少讨论。 我们建议更多地考虑到AHA声明中强调的那些强调的盐敏感性的概念框架和理论可能有助于推进盐诱导的血压增加的发病机制,结果可能导致预防和治疗的改进方法 这种常见的疾病。

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