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首页> 外文期刊>Journal of Hand Surgery. American Volume >Impact of Variation of Corticosteroid Dose, Injection Site, and Multiple Injections on Blood Glucose Measurement in Diabetic Patients
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Impact of Variation of Corticosteroid Dose, Injection Site, and Multiple Injections on Blood Glucose Measurement in Diabetic Patients

机译：皮质类固醇剂量，注射部位和多次注射对糖尿病患者血糖测量的影响

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PurposeThis study examined how corticosteroid dose, injection site location, and patient demographics affect blood glucose level after corticosteroid injection in diabetic patients. MethodsWe prospectively enrolled 70 patients with diabetes mellitus requiring upper- and/or lower-extremity corticosteroid injections. Patients measured fasting and postprandial blood glucose for 14 days after the injection. Blood glucose from days 1 through 7 was compared with the average of days 10 through 14, acting as control. Changes in blood glucose were compared by corticosteroid dose, injection location, patient demographics, and insulin use. ResultsPatients who underwent shoulder, wrist, or hand injections and patients who received multiple injections had no significant elevations in fasting or postprandial blood glucose, whereas those with knee injections had a significant increase in fasting blood glucose on postinjection days 1 and 2. Preinjection hemoglobin A1C had a significant effect on postinjection blood glucose whereas corticosteroid dose, body mass index, insulin use, and the number of injections had no significant effect on the elevation of blood glucose. There were no cases of diabetic ketoacidosis in any subjects. ConclusionsPatients receiving corticosteroid injections in the upper extremity did not experience significant increases in blood glucose whereas those undergoing knee corticosteroid injections demonstrated elevated blood glucose levels. Because poorer glucose control was associated with greater elevations in blood glucose after injection, patients with higher hemoglobin A1C should be counseled to monitor postinjection glucose more closely. Type of study/level of evidenceTherapeutic II.
机译：目的研究检测了皮质类固醇剂量，注射部位位置和患者人口统计学如何影响糖尿病患者皮质类固醇注射后的血糖水平。方法对期招待70名糖尿病患者需要上下和/或下肢皮质类固醇注射。患者在注射后14天测量禁食和餐后血糖。将血糖从第1〜至7天的血糖与第10天至14天的平均值进行比较，作为对照。通过皮质类固醇剂量，注射位置，患者人口统计和胰岛素使用比较血糖的变化。接受肩部，手腕或手腕注射和接受多次注射的患者的结果在禁食或餐后血糖中没有显着的升高，而膝关节注射的人在出现的时期1和2.预示出血红蛋白A1C中的血葡萄糖的血糖显着增加对假发血糖有显着影响，而皮质类固醇剂量，体重指数，胰岛素使用以及注射次数对血糖的升高没有显着影响。任何受试者都没有糖尿病酮症病例。结论上肢接受皮质类固醇注射的剂量没有经历血糖的显着增加，而那些患者皮质类固醇注射的血糖水平升高。由于注射后血糖中较差的葡萄糖控制较差，所以应咨询血红蛋白A1C更高的患者，以更密切地监测出关注葡萄糖。 EVIVENTHEREREAPTIC II的研究类型/水平。

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