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首页> 外文期刊>Journal of pediatric psychology >The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis.
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The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis.

机译：对非甾体抗炎药，甲氨蝶呤或类固醇的影响对健康相关的生活质量的影响，治疗少年特发性关节炎。

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OBJECTIVE: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). METHODS: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. RESULTS: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. CONCLUSION: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.
机译：目的：评估和比较少年发作性关节炎儿童健康相关生活质量（HRQOL），家族功能和医疗状况的影响和比较。 方法：通过儿科病毒学评估均为JIA的五十七种儿童，并入三个治疗组中的一种：（1）非甾体类抗炎; （2）甲氨蝶呤; 或（3）通过IV甲基己酮醇的类固醇。 问卷在基线和4个月的随访中进行。 参加的儿科风湿病学提供额外的医疗信息。 结果：数据记录佳对HRQOL的影响，特别是在物理和疼痛域名。 虽然报告了更多的副作用问题，但类固醇患者在相对于其他群体的随访中经历了改善的HRQOL。 结论：这些结果表明类固醇在治疗贾儿童的积极益处，尽管不良副作用的发病率最大。

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