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首页> 外文期刊>American journal of clinical dermatology >Can we define acne as a chronic disease? If so, how and when?
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Can we define acne as a chronic disease? If so, how and when?

机译：我们可以将痤疮定义为慢性疾病吗？如果是这样，如何以及何时？

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There is widespread misunderstanding of acne amongst both the medical and lay community, who often perceive the condition to be a simple, self-limited affliction of adolescents. Because many think that the disease "will go away on its own," they do not feel an urgency to aggressively treat acne. However, very often the reality is that acne treatment can be quite difficult. Furthermore, acne can be a devastating disease for the patient, since it manifests on visible body parts and in children near puberty, who are vulnerable both socially and psychologically. Most typically, acne is not an acute disease but rather a condition that continuously changes in its distribution and severity. Usually, acne treatment is necessary for many months and sometimes years. Despite treatment, acne may cause scarring and associated negative psychological effects. It is important for both patients and physicians to be aware that very effective treatments are available. It is also important to realize that new studies have proven the benefit of maintenance therapy with topical retinoids; these agents can minimize the potential for relapse, which is part of the natural history of acne. This article reviews the evidence suggesting that acne is a chronic disease in at least a subset of individuals. The members of the Global Alliance to Improve Outcomes in Acne believe that acne should be recognized and investigated as a chronic disease. This will change expectations of clinical trial design and treatment and will highlight gaps in the knowledge of acne epidemiology. The result should be an improvement in patient outcomes.
机译：在医学界和外行社区中，人们对粉刺普遍存在误解，他们通常认为痤疮是一种简单的，自我限制的青少年疾病。因为许多人认为这种疾病“会自行消失”，所以他们并不急于积极治疗痤疮。但是，现实常常是痤疮治疗非常困难。此外，痤疮对患者可能是毁灭性的疾病，因为它出现在可见的身体部位以及青春期附近的儿童中，这些儿童在社交和心理上都容易受到伤害。最典型的是，痤疮不是一种急性疾病，而是一种其分布和严重程度不断变化的疾病。通常，痤疮治疗需要几个月甚至几年的时间。尽管治疗，痤疮可能会导致疤痕形成和相关的负面心理影响。对于患者和医生而言，重要的是要意识到非常有效的治疗方法是很重要的。同样重要的是要认识到新的研究已经证明了使用局部类维生素A维持治疗的益处。这些药物可以将复发的可能性降到最低，这是痤疮自然病史的一部分。本文回顾了表明痤疮是至少一部分个体的慢性疾病的证据。全球改善痤疮结局联盟的成员认为，痤疮应作为一种慢性病得到认可和调查。这将改变对临床试验设计和治疗的期望，并将突出痤疮流行病学知识的空白。结果应该是患者预后的改善。

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