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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Sex Differences in Stroke Incidence in a Portuguese Community-Based Study
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Sex Differences in Stroke Incidence in a Portuguese Community-Based Study

机译:葡萄牙社区研究中风发病率的性差异

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Background and AimStroke is a major health problem. Several studies reported sex differences regarding stroke. We aim to study this issue in an incidence stroke study. MethodsData were retrieved from a community-based prospective register of patients that had a first ever stroke in a life time between October 2009 and September 2011. We studied sex differences regarding demographic data, vascular risk factors, stroke type, stroke severity (NIHSS), disability at 28days (modified Rankin scale (mRS)), and case fatality at 30 and 90days. ResultsFrom 720 stroke patients, 45.3% were men. Women were older (75.0 ± 13.6 versus 67.2 ± 14.9 years), had a worse premorbid mRS (39.3% versus 25.5%,P< .001), and a higher prevalence of hypertension (P?=?.004) and atrial fibrillation (P< .001). Previous myocardial infarction was more frequent in men (P?=?.001), as well as smoking habits (P< .001). Ischemic stroke was more common in women than men (87.6% versus 81.3%,P?=?.038). The 28 days’ outcome was worse in women (mRS ≥ 2, 77.2% versus 70.6%,P?=?.044). No differences were found in initial stroke severity (median NIHSS?=?4) and case fatality at 30 and 90days, after adjusting for age and premorbid mRS. ConclusionNo differences were found in stroke initial severity and mortality at 30 and 90days between men and women, despite the sex differences pertaining to the stroke profile—age, vascular risk factors, stroke type, and outcome. Our results are somewhat discrepant from those described in the literature; more research is needed to understand if this may be due to changes in stroke standard of care.
机译:背景和Aimstrore是一个主要的健康问题。几项研究报告了关于中风的性别差异。我们的目标是在发病卒中研究中研究这个问题。方法从2009年10月和2011年9月的一生中曾经有一段时间的患者进行了一系列患者的患者检索了方法。我们研究了关于人口统计数据,血管危险因素,中风类型,中风严重程度(NIHSS)的性差异, 28天的残疾(修改Rankin规模(MRS)),以及30日和90天的病例。结果以720卒中患者,45.3%是男性。女性年龄较大(75.0±13.6与67.2±14.9岁),具有较差的前置MRS(39.3%对25.5%,P <.001),高血压患病率更高(P?= 004)和心房颤动( p <.001)。以前的心肌梗死在男性中更频繁(p?= 001),以及吸烟习惯(p <.001)。缺血性卒中在女性中比男性更常见(87.6%对81.3%,p?= 038)。 28天的结果在女性中更差(≥2,77.2%与70.6%,p?= 044)。在调整年龄和预血管MRS后,初始中风严重程度(中位数NIHSS?= 4)以及30和90天的病例没有发现差异。结论在男女和女性之间的30和90天在30和90天的中风初始严重程度和死亡率中发现了差异,尽管与中风概况,血管危险因素,中风类型和结果有关。我们的结果与文献中描述的结果有些差异;需要更多的研究来了解这可能是由于行程护理标准的变化。

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