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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Vascular Parkinsonism in a Tertiary Care Stroke Prevention Clinic and the Development of a New Screening Strategy
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Vascular Parkinsonism in a Tertiary Care Stroke Prevention Clinic and the Development of a New Screening Strategy

机译：血管帕金森主义在第三节护理冲程预防诊所和新的筛查策略的发展

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Objectives: To determine the prevalence of vascular parkinsonism (VasP) in a stroke prevention clinic (SPC). Background: VasP can be defined by an onset of parkinsonism with prominent gait problems occurring within 1 year of stroke. Methods: We created a screening strategy based on the Tanner Questionnaire (TQ), a validated scale for parkinsonism, and the creation of a 4-point Five-Minute Assessment Scale (FMAS) operationalizing Zijlmans' criteria for the diagnosis of VasP. Consecutive stroke patients were screened over a 12-month period using the TQ and the FMAS. SAS statistical software was used. Results: Two hundred forty patients (52.5% females) were screened (mean age of 65 years, standard deviation, 14.5). Twenty-five percent of patients had a TQ score = 4 with a median FMAS of 2. In this group, 32.6% (15/46) were found to have parkinsonism. Seventeen percent (8/46) were diagnosed with VasP having an FMAS of 4. Seventy-five of the participants obtained a TQ = 3, with a median FMAS of 1. Only 1 patient in this group had parkinsonism (1.9%; 1/194). Using a cutoff of 4 points in the TQ resulted in a sensitivity of 93.8%, a specificity of 86.2% for parkinsonism, and a sensitivity of 100% with a specificity of 83% for VasP. Patients with FMAS = 4 (VasP) attained higher scores in the TQ with a median of 5 (Spearman rank correlation coefficient for the TQ and the FMAS =.447, P .0005). Conclusions: We documented a prevalence of 3% (8/240) for VasP in an SPC. We propose a new, easier, and unified 2-step TQ-FMAS screening strategy for this condition.
机译：目的：确定血管帕金森主义（VASP）在卒中预防诊所（SPC）中的患病率。背景：VASP可以通过帕金森主义的发病来定义，并且在笔划的1年内发生了突出的步态问题。方法：我们创建了基于Tanner调查问卷（TQ）的筛选策略，帕金森主义的验证规模，并创建了4分五分钟的评估量表（FMA）运作Zijlmans的诊断标准，用于诊断VASP。使用TQ和FMA的12个月内筛选连续的中风患者。使用SAS统计软件。结果：筛选两百四十名患者（52.5％的女性）（平均年龄为65岁，标准差，14.5）。二十五名患者的患者进行了TQ得分。= 4 = 4中位数为2.在本集团中，发现32.6％（15/46）有帕金森主义。将百分比（8/46）诊断为具有4.七十五个参与者的FMA的VASP获得了TQ＆ 3，中位为1.该组中只有1名患者的帕金森（1.9％; 1/194）。在TQ中使用4分的截止导致灵敏度为93.8％，帕金森主义的特异性为86.2％，敏感度为100％，vasp的特异性为83％。患有FMAS = 4（VASP）的患者在TQ中获得了更高的分数，中位数为5（SPEARMAN秩相关系数，TQ和FMAS = .447，P＆ .0005）。结论：我们记录了SPC中vasp的3％（8/240）的患病率。我们为这种情况提出了一个新的，更容易和统一的2步TQ-FMAS筛选策略。

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