首页> 外文期刊>Journal of structural chemistry >Novel Phthalocyanines Containing Guaiacol Azo Dyes: Synhthesis, Antioxidant, Antibacterial, and Anticancer Activity
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Novel Phthalocyanines Containing Guaiacol Azo Dyes: Synhthesis, Antioxidant, Antibacterial, and Anticancer Activity

机译:含Guaiacol Azo染料的新型酞菁:斜度,抗氧化剂,抗菌和抗癌活性

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摘要

In an attempt to understand the antibacterial, antioxidant, and anticancer properties of phthalocyanines containing azo dye, new metallophthalocyanines (M: Mn, Co, Zn) substituted with guaiacol azo dyes are described. The high DPPH scavenging and ferrous ion chelating activity are obtained from almost all compounds. All compounds exhibit a poor antibacterial activity against the studied bacteria. Cytotoxicity, apoptotic and necrotic effects are examined on human breast cancer cells (MCF-7) and fibroblast cells. It is determined that methoxy groups at newly synthesized compounds increase the antioxidant property but decrease other antibacterial and anticancer properties.
机译:试图了解含有偶氮染料的酞菁的抗菌,抗氧化剂和抗癌性质,描述被用愈胶醇偶氮染料取代的新金属酞菁(M:Mn,Co,Zn)。 高DPPH清除和亚铁离子螯合活性是几乎所有化合物获得的。 所有化合物对研究的细菌抗菌活性差。 在人乳腺癌细胞(MCF-7)和成纤维细胞上检查细胞毒性,凋亡和坏死作用。 确定新合成化合物的甲氧基增加抗氧化性能,但减少其他抗菌和抗癌性质。

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