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首页> 外文期刊>Journal of studies on alcohol and drugs. >Anxiety Sensitivity and Nicotine Replacement Therapy Side Effects: Examining the Role of Emotion Dysregulation Among Treatment-Seeking Smokers
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Anxiety Sensitivity and Nicotine Replacement Therapy Side Effects: Examining the Role of Emotion Dysregulation Among Treatment-Seeking Smokers

机译：焦虑敏感性和尼古丁替代疗法副作用：检查情感失调在寻求吸烟者中的情感失调作用

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Objective: Nicotine replacement therapy (NRT) significantly increases the likelihood of quit success at least over the short term, yet some smokers prematurely discontinue use. NRT side effects are often cited as the primary reason for medication discontinuation. The current study examined a theoretical pathway by which two smoking-related emotional vulnerabilities (anxiety sensitivity and emotion dysregulation) were related to the number of NRT (nicotine patch) side effects reported 1 week following a scheduled quit attempt. It was hypothesized that anxiety sensitivity would have an indirect effect on NRT side effects through emotion dysregulation. Method: A total of 179 treatment-seeking, adult daily smokers with elevated anxiety sensitivity (47.5% male; M age = 39.73 years, SD = 13.87) were enrolled in a smoking cessation trial. Results: Covariate-adjusted analyses provided support for the hypothesized pathway, such that emotion dysregulation explained the association between anxiety sensitivity and NRT side effects (b = 0.02, SE = 0.01, 95% CI [0.002, 0.03]; completely standardized estimate = .15). Conclusions: The findings underscore the importance of developing cessation treatments that incorporate techniques to enhance emotion regulation, particularly among smokers higher in anxiety sensitivity, to decrease the risk of NRT side effects.
机译：目的：尼古丁替代治疗（NRT）至少在短期内显着增加退出成功的可能性，但一些吸烟者过早停止使用。 NRT副作用通常被引用为药物停止的主要原因。目前的研究检测了一种理论途径，其吸烟相关的情绪脆弱性（焦虑敏感性和情感呼吸困难）与预定退出尝试后1周报告的NRT（尼古丁补丁）副作用的数量有关。假设焦虑敏感性对通过情感失调对NRT副作用的间接影响。方法：共有179名寻求治疗，成年人每日吸烟者高焦虑敏感性（男性47.5％= 39.73岁，SD = 13.87）均被入选吸烟戒烟试验。结果：调整调整的分析提供了对假设途径的支持，使得情绪失呼率解释了焦虑敏感性和NRT副作用之间的关联（B = 0.02，Se = 0.01,95％Ci [0.002,0.03];完全标准化估计=。 15）。结论：调查结果强调了制定渗透治疗的重要性，该治疗掺入技术以增强情绪调节，特别是吸烟者在焦虑敏感性的吸烟者中，降低NRT副作用的风险。

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