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首页> 外文期刊>Journal of Veterinary Research >Occurrence and distribution of canine cutaneous mast cell tumour characteristics among predisposed breeds
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Occurrence and distribution of canine cutaneous mast cell tumour characteristics among predisposed breeds

机译：倾斜品种犬皮肤肥大细胞肿瘤特征的发生和分布

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Introduction: Breed predisposition to cutaneous mast cell tumours (MCT) in a population of dogs in Poland affected by various skin tumours was assessed, and the distribution of MCT characteristics such as histological grading, sex, age, and location, in predisposed breeds was evaluated. Material and Methods: The retrospective epidemiological study included 550 dogs affected by cutaneous MCTs with a reference group of 2,557 dogs diagnosed with other skin tumours. Results: A univariable logistic regression analysis was performed to determine the odds ratios (ORs) with 95% confidence intervals. The risk of high-grade MCTs was the highest for Shar-Peis (OR: 26.394) and American Staffordshire Terriers (OR: 2.897). Boxers (OR: 6.619), Labrador Retrievers (OR: 2.630), French Bulldogs (OR: 2.050), Golden Retrievers (OR: 1.949), and American Staffordshire Terriers (OR: 2.592) were mainly affected by low-grade MCTs. The high risk of MCT was calculated to be at the age of 4-6 years for Labrador Retrievers (OR: 2.686) and 7-10 years for Boxers (OR: 2.956) and French Bulldogs (OR: 9.429). MCTs were significantly more often located on the trunk in French Bulldogs (OR: 4.680), American Staffordshire Terriers (OR: 2.520), and Labrador Retrievers (OR: 1.948). There was no statistically significant correlation between gender and the occurrence of MCTs in the breeds. Conclusions: The breed-predicated differences in the clinical course of MCTs suggest a genetic background for the tumours.
机译：介绍：评估了由各种皮肤肿瘤影响的波兰犬群中皮肤肥大细胞肿瘤（MCT）的促进易感性，并评估了在倾斜品种中的组织学分级，性别，年龄和地点等MCT特征的分布。材料和方法：回顾性流行病学研究包括受皮肤MCT影响的550只狗，其中2,557只狗被诊断为其他皮肤肿瘤。结果：进行了不可变化的逻辑回归分析，以确定具有95％置信区间的差距（或者）。高档MCTS的风险是Shar-Peis（或：26.394）和美国斯塔福德郡梗（或：2.897）的最高风险。拳击手（或：6.619），拉布拉多犬权（或：2.630），法国斗牛犬（或：2.050），金色猎犬（或：1.949）和美国斯塔福德郡梗犬（或：2.592）主要受低级MCT的影响。 MCT的高风险计算为4-6岁，为拉布拉多检索（或：2.686）和7-10岁的拳击手（或：2.956）和法国斗牛犬（或：9.429）。 MCTS更常见于法国斗牛犬（或：4.680），美国斯塔福德郡梗（或：2.520）和拉布拉多猎犬（或：1.948）的行李箱。性别与品种中的MCTS之间没有统计学上的相关性。结论：MCT临床过程中的品种预测差异表明肿瘤的遗传背景。

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