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Analysis of factors correlated with insulin administration in patients with gestational diabetes mellitus in the Liaoning region

机译：辽宁地区妊娠期糖尿病患者胰岛素施用的因素分析

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To investigate the factors correlated with insulin administration in patients with gestational diabetes mellitus (GDM). Methods: This was a controlled study including women in the Liaoning region who were diagnosed with GDM in Shengjing Hospital of China Medical University and followed up until parturition from 2011 to 2015; 93 women with complete data who met the inclusion criteria were eventually enrolled. Pregnant women only requiring dietary and exercise therapy to maintain blood glucose in the normal range were included in the control group (n = 52); pregnant women whose blood glucose remained abnormal despite dietary and exercise therapy and required additional insulin to normalize blood glucose made up the insulin group (n =41). Various indicators, including age, FBG, OGTT1hBG, OGTT2hBG and GA at initial diagnosis of GDM, pregestational BMI, family DM history, and jugular and axillary acanthosis nigricans, were also compared between the two groups and related to the blood glucose level in the third trimester. A logistic regression model was established with insulin use during pregnancy being the dependent variable and age, family DM history, jugular and axillary acanthosis nigricans, FBG, and OGTT1hBG being the independent variables. An ROC curve was used to determine the thresholds of FBG Conclusions: Among pregnant women with GDM, those with an age greater than 33 years old, family DM history, jugular and axillary acanthosis nigricans, FBG>5.6 mmol/L or OGTT1hBG>11.1 mmol/L would be more likely to require insulin administration to normalize blood glucose. FBG>5.6 mmol/L is the most important factor for predicting pregnant women who need insulin treatment to target blood glucose.
机译：探讨妊娠期糖尿病（GDM）患者胰岛素给药相关的因素。方法：这是一项受控研究，包括辽宁地区的妇女，他被诊断患有中国医科大学盛静医院的GDM，并从2011年到2015年的份额进行跟进; 93符合符合纳入标准的完整数据的妇女最终入学。仅需要膳食和运动疗法以维持正常范围内血糖的孕妇包括在对照组（n = 52）中;尽管膳食和运动疗法以及需要额外的胰岛素，血糖仍然异常的孕妇，以使血糖标准化胰岛素基团（n = 41）。在两组之间也比较了两组和颈术和颈宫和腋生刺眼的核心和腋生和腋生刺眼的初步诊断的各种指标，包括年龄，FBG，OGTT1HBG，OGTTT2HBG和GA。三个月。在怀孕期间建立了一种逻辑回归模型，是孕胰岛素使用，是依赖变量和年龄，家庭DM历史，颈颈菌和腋生核心，FBG和OGTT1HBG是独立变量。 ROC曲线用于确定FBG结论的阈值：孕妇中的GDM，年龄超过33岁的人，家庭DM历史，颈颈菌，颈癌尼霉菌，FBG> 5.6mmol / L或OGTTT1HBG> 11.1mmol / L更有可能需要胰岛素给药来标准化血糖。 FBG> 5.6mmol / L是预测需要胰岛素治疗以靶向血糖的孕妇最重要的因素。

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