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首页> 外文期刊>Biotechnology Advances: An International Review Journal >Highlights of recent developments and trends in cancer nanotechnology research-View from NCI Alliance for Nanotechnology in Cancer
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Highlights of recent developments and trends in cancer nanotechnology research-View from NCI Alliance for Nanotechnology in Cancer

机译：癌症纳米技术研究的最新进展和趋势摘要-NCI癌症纳米技术联盟的观点

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Although the incidence of cancer and cancer related deaths in the United States has decreased over the past two decades due to improvements in early detection and treatment, cancer still is responsible for a quarter of the deaths in this country. There is much room for improvement on the standard treatments currently available and the National Cancer Institute (NCI) has recognized the potential for nanotechnology and nanomaterials in this area. The NCI Alliance for Nanotechnology in Cancer was formed in 2004 to support multidisciplinary researchers in the application of nanotechnology to cancer diagnosis and treatment. The researchers in the Alliance have been productive in generating innovative solutions to some of the central issues of cancer treatment including how to detect tumors earlier, how to target cancer cells specifically, and how to improve the therapeutic index of existing chemotherapies and radiotherapy treatments. Highly creative ideas are being pursued where novelty in nanomaterial development enables new modalities of detection or therapy. This review highlights some of the innovative materials approaches being pursued by researchers funded by the NCI Alliance. Their discoveries to improve the functionality of nanoparticles for medical applications includes the generation of new platforms, improvements in the manufacturing of nanoparticles and determining the underlying reasons for the movement of nanoparticles in the blood
机译：尽管由于早期发现和治疗的改善，在美国，癌症和与癌症相关的死亡的发生率在过去的二十年中有所下降，但癌症仍占美国死亡人数的四分之一。目前可用的标准治疗方法还有很大的改进空间，美国国家癌症研究所（NCI）已经认识到纳米技术和纳米材料在该领域的潜力。 NCI癌症纳米技术联盟成立于2004年，旨在支持多学科研究人员将纳米技术应用于癌症的诊断和治疗。该联盟的研究人员在为癌症治疗的一些核心问题提供创新解决方案方面卓有成效，这些解决方案包括如何及早发现肿瘤，如何特异性靶向癌细胞以及如何提高现有化学疗法和放射疗法的治疗指数。在纳米材料开发的新颖性可以实现新的检测或治疗方法的情况下，正在追求极富创意的想法。这篇评论重点介绍了由NCI联盟资助的研究人员正在追求的一些创新材料方法。他们为改善医疗应用中纳米颗粒的功能性而进行的发现包括生成新平台，改进纳米颗粒的生产以及确定纳米颗粒在血液中运动的根本原因。

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