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首页> 外文期刊>Allergy >Added sensitivity of component-resolved diagnosis in hymenoptera venom-allergic patients with elevated serum tryptase and/or mastocytosis
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Added sensitivity of component-resolved diagnosis in hymenoptera venom-allergic patients with elevated serum tryptase and/or mastocytosis

机译:血膜色氨酸升高和/或肥大细胞增多症的膜翅目毒敏患者增加了成分分辨诊断的敏感性

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Background: Anaphylaxis caused by hymenoptera venom allergy is associated with elevation of baseline serum tryptase (sBT) and/or mastocytosis in about 5% of patients. Up to now, no information has become available on single venom allergen sIgE reactivity and the usefulness of component-resolved approaches to diagnose this high-risk patient group. To address the component-resolved sIgE sensitization pattern and diagnostic sensitivity in hymenoptera venom-allergic patients with elevated sBT levels and/or mastocytosis, a panel of yellow jacket and honeybee venom allergens was applied on a widely used IgE immunoassay platform.
机译:背景:由膜翅目毒液过敏引起的过敏反应与基线血清类胰蛋白酶(sBT)升高和/或肥大细胞增多症有关,约占5%。到目前为止,尚无关于单一毒变应原sIgE反应性和成分解析方法对这种高危患者组的诊断有用的信息。为了解决在sBT水平升高和/或肥大细胞增多症的膜翅目变​​态反应性过敏患者中的sIgE致敏模式和诊断敏感性,在广泛使用的IgE免疫测定平台上应用了一组黄色外套和蜜蜂毒变应原。

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