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Analysis of Kidney Biopsy Data From a Single Center in the Midland Rural Area of China, 1996-2010

机译：1996-2010年中国中部农村地区单中心肾脏活检数据分析

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Objective: To survey the clinical epidemiology and correlations between pathology and clinical features of major groups of kidney diseases in a rural area of China.Methods: From January 1996 to December 2010, histologic diagnosis of renal disease was made on samples collected from 919 patients from a single center in the midland rural area of China. Demographic data were obtained from all patients, and clinical profiles were analyzed in 917 patients. Results: The mean age of the whole group was 33.13 (14.13) years (range 16-72 years). Men accounted for 55.28% (n = 508) and women made up 45.72% (n = 408). Patients aged 16 to 50 years comprised 83.75% of the sample (n = 770). Lupus nephritis was the predominant diagnosis in women; renal diseases were predominant in men. In patients with nephrotic syndrome, mesangial proliferative glomerulonephritis was the most frequent pathologic pattern (39.46%), followed by IgA nephropathy (18.39%), whereas in patients with nephritic syndrome, IgA nephropathy (39.64%) was the most frequent pathologic pattern, followed by mesangial proliferative glomerulonephritis (32.38%). The most common pathologic pattern in patients with secondary glomerulonephritis was Henoch-Schonlein purpura nephritis, followed by lupus nephritis.Conclusions: Mesangial proliferative glomerulonephritis was the most common renal pathologic pattern. Male adolescents were predominant in this group of patients. The most common clinical syndrome was nephrotic syndrome.
机译：目的：调查中国农村地区主要人群肾脏疾病的临床流行病学及病理学与临床特征的相关性。方法：从1996年1月至2010年12月，对919例来自中国的肾病患者进行组织学诊断。中国中部农村地区的一个中心。从所有患者中获得人口统计学数据，并对917例患者的临床资料进行分析。结果：整个组的平均年龄为33.13（14.13）岁（范围16-72岁）。男性占55.28％（n = 508），女性占45.72％（n = 408）。 16至50岁的患者占样本的83.75％（n = 770）。狼疮性肾炎是女性的主要诊断。肾脏疾病以男性为主。在肾病综合征患者中，肾小球膜增生性肾小球肾炎是最常见的病理模式（39.46％），其次是IgA肾病（18.39％），而在肾病综合征患者中，IgA肾病（39.64％）是最常见的病理模式，其次系膜增生性肾小球肾炎（32.38％）。继发性肾小球肾炎患者最常见的病理类型是过敏性紫癜性肾炎，其次是狼疮性肾炎。结论：肾小球系膜增生性肾小球肾炎是最常见的肾脏病理类型。在这一组患者中，男性青少年占主导地位。最常见的临床综合征是肾病综合征。

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