...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ACS combinatorial science >Leuckart-Wallach Route Toward Isocyanides and Some Applications
【24h】

Leuckart-Wallach Route Toward Isocyanides and Some Applications

机译：Leuckart-Wallach通往异氰酸酯的路线及一些应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Isocyanide-based multicomponent reactions (IMCR) are among the most important chemical reactions to efficiently generate molecular diversity and have found widespread use in industry and academia. Generally, isocyanides are synthesized in 1-2 steps starting from primary amines. Here, we provide experimental detail on an alternative approach toward formamides and, thus, isocyanides via the Leuckart-Wallach reaction in an improved variation. The resulting >50 synthesized and characterized formamides are useful starting materials for IMCR, as well as other chemistries. The advantage of using the Leuckart-Wallach pathway to formamides and isocyanides is the lower price, on average, of the starting materials, as well as their differential and complementary structural diversity, as compared to the primary amine pathway.
机译：基于异氰化物的多组分反应（IMCR）是有效产生分子多样性的最重要的化学反应之一，已在工业和学术界得到广泛应用。通常，异氰酸酯从伯胺开始以1-2个步骤合成。在这里，我们提供了通过Leuckart-Wallach反应以改进的形式制备甲酰胺和异氰化物的另一种方法的实验细节。所得的> 50合成并表征的甲酰胺是IMCR以及其他化学方法的有用原料。与伯胺途径相比，使用Leuckart-Wallach途径合成甲酰胺和异氰化物的优点是平均而言原料的价格更低，以及它们的差异和互补结构多样性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号