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Establishing equivalence: Methodological progress in group-matching design and analysis

机译:建立等效性:小组匹配设计和分析的方法学进展

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摘要

This methodological review draws attention to the challenges faced by intellectual and developmental disabilities researchers in the appropriate design and analysis of group comparison studies. We provide a brief overview of matching methodologies in the field, emphasizing group-matching designs used in behavioral research on cognition and language in neurodevelopmental disorders, including autism spectrum disorder, Fragile X syndrome, Down syndrome, and Williams syndrome. The limitations of relying on p values to establish group equivalence are discussed in the context of other existing methods: equivalence tests, propensity scores, and regression-based analyses. Our primary recommendation for advancing research on intellectual and developmental disabilities is the use of descriptive indices of adequate group matching: effect sizes (i.e., standardized mean differences) and variance ratios.
机译:这项方法学综述提请人们注意智力和发育障碍研究人员在适当设计和分析小组比较研究中所面临的挑战。我们简要概述了该领域的匹配方法,重点介绍了在神经发育障碍(包括自闭症谱系障碍,脆性X综合征,唐氏综合征和Williams综合征)的认知和语言行为研究中使用的群体匹配设计。在其他现有方法的上下文中讨论了依赖p值建立组等效性的局限性:等效性检验,倾向评分和基于回归的分析。我们进行智力和发育障碍研究的主要建议是使用描述性指标来进行适当的群体匹配:效果大小(即标准化均值差)和方差比。

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