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An audit of the haemodynamic and emergence characteristics of single-shot 'ketofol'

机译：单次“酮酚”血流动力学和出现特征的审核

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摘要

'Ketofol', the single-syringe combination of ketamine and propofol (50 mg of ketamine and 90 mg of propofol in a 10 ml syringe) is becoming increasingly popular for short procedures, progressively replacing the more traditional use of ketamine and diazepam in some settings. This audit examined the haemodynamic, emergence and other characteristics of ketofol administration in 42, otherwise fit, women undergoing bilateral post-partum tubal ligation at Vila Central Hospital in Vanuatu. The combination of ketamine and propofol had no clinically important adverse haemodynamic effects. Wake-up from ketofol was favourable, with low rates of nausea and minimal emergence delirium. However, 43% of patients required airway support. For short procedures such as post-partum tubal ligation in fit patients, ketofol appears to have minimal adverse haemodynamic effects and favourable emergence characteristics.
机译：氯胺酮和丙泊酚的单针组合“ Ketofol”（在10 ml注射器中使用50 mg氯胺酮和90 mg异丙酚）在短时间操作中正变得越来越流行，在某些情况下逐渐取代了较传统的氯胺酮和地西epa用法。这项审核检查了42名在瓦努阿图维拉中心医院接受产后双侧输卵管结扎术的女性（其他情况适合）中酮可酚给药的血流动力学，出现情况和其他特征。氯胺酮和丙泊酚的组合没有临床上重要的不良血流动力学影响。从ketofol唤醒是有利的，恶心发生率低，出现ir妄最少。但是，有43％的患者需要气道支持。对于短期手术（如适合患者的产后输卵管结扎术）而言，ketofol似乎具有最小的不良血流动力学影响和良好的出现特征。

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