Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents.

Li WS; More SV; Wang C

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Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents.

机译：新型呋唑-3,4-酰胺类似物作为有效抗癌剂的合成与结构 - 活性关系。

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This study describes the synthesis and structure-activity relationships of a series of furazan-3,4-diamide analogs. 1,2,5-Oxadiazole ring and electron-withdrawing substituent on the phenyl ring are proposed to be the important elements which contribute to a significant extent maximal potency of anti-proliferation effect.

机译：本研究描述了一系列呋唑-3,4-一致类似物的合成和结构 - 活性关系。提出了苯环上的1,2,5-氧代唑环和电子取代基取代基，成为有助于抗扩散效应的显着效力的重要因素。

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《Bioorganic and Medicinal Chemistry Letters》 |2010年第3期|共5页
作者
Li WS; More SV; Wang C;
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Institute of Chemistry Academia Sinica Taipei 115 Taiwan.;

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正文语种 eng
中图分类药学;生物化学;
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机译：新型呋唑-3,4-酰胺类似物作为有效抗癌剂的合成与结构 - 活性关系。
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Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents.

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