...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ACS applied materials & interfaces >Influence of the Aliphatic Side Chain on the Near Atmospheric Pressure Plasma Polymerization of 2-Alkyl-2-oxazolines for Biomedical Applications
【24h】

Influence of the Aliphatic Side Chain on the Near Atmospheric Pressure Plasma Polymerization of 2-Alkyl-2-oxazolines for Biomedical Applications

机译：脂族侧链对近大气压血浆聚合对2-烷基-2-恶唑碱的影响生物医学应用

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Plasma polymerization is gaining popularity as a technique for coating surfaces due to the low cost, ease of operation, and substrate-independent nature. Recently, the plasma polymerization (or deposition) of 2-oxazoline monomers was reported resulting in coatings that have potential applications in regenerative medicine. Despite the structural versatility of 2-oxazolines, only a few monomers have been subjected to plasma polymerization. Within this study, however, we explore the near atmospheric pressure plasma polymerization of a range of 2-oxazoline monomers, focusing on the influence of the aliphatic side-chain length (methyl to butyl) on the plasma polymerization process conditions as well as the properties of the obtained coatings. While side-chain length had only a minor influence on the chemical composition, clear effects on the plasma polymerization conditions were observed, thus gaining valuable insights in the plasma polymerization process as a function of monomer structure. Additionally, cytocompatibility and cell attachment on the coatings obtained by 2-oxazoline plasma polymerization was assessed. The coatings displayed strong cell interactive properties, whereby cytocompatibility increased with increasing aliphatic side-chain length of the monomer, reaching up to 93% cell viability after 1 day of cell culture compared to tissue culture plates. As this is in stark contrast to the antifouling behavior of the parent polymers, we compared the properties and composition of the plasma-polymerized coatings to the parent polymers revealing that a significantly different coating structure was obtained by plasma polymerization.
机译：等离子体聚合是由于由于低成本，易于操作和底物无关的性质而导致涂覆表面的技术。最近，据报道了2-恶唑啉单体的血浆聚合（或沉积），导致涂层具有潜在的再生药物。尽管2-恶唑啉的结构多种能力，但仅对少数单体进行了血浆聚合。然而，在该研究中，我们探讨了一系列2-恶唑啉单体的接近大气压等离子体聚合，聚焦脂族侧链长度（甲基丁基）对血浆聚合过程条件以及性质的影响得到的涂层。虽然侧链长度对化学成分仅有次要影响，但观察到对血浆聚合条件的明显影响，因此在血浆聚合过程中获得了作为单体结构的函数的有价值的见解。另外，评估通过2-恶唑啉血浆聚合获得的涂层上的细胞织立性和细胞附着。涂层显示出强细胞互动性质，从而随着单体的脂族侧链长度的增加而增加，与组织培养板相比，在细胞培养物的1天后达到高达93％的细胞活力增加。由于这与母体聚合物的防污行为形成鲜明对比，因此将等离子体聚合涂层的性质和组合物与母体聚合物进行了比较，显示通过血浆聚合获得显着不同的涂层结构。

著录项

  • 来源
    《ACS applied materials & interfaces》 |2019年第34期|共11页
  • 作者

    Van Guyse Joachim F. R.; Cools Pieter; Egghe Tim; Asadian Mahtab; Vergaelen Maarten; Rigole Petra; Yan Wenqing; Benetti Edmondo M.; Jerca Valentin-Victor; Declercq Heidi; Coenye Tom; Morent Rino; Hoogenboom Richard; De Geyter Nathalie;

  • 作者单位

    Univ Ghent Dept Organ &

    Macromol Chem Supramol Chem Grp Ctr Macromol Chem CMaC Fac Sci Krijgslaan 281 S4 B-9000 Ghent Belgium;

    Univ Ghent Dept Appl Phys RUPT Fac Engn &

    Architecture Sint Pietersnieuwst 41 B4 B-9000 Ghent Belgium;

    Univ Ghent Dept Organ &

    Macromol Chem Supramol Chem Grp Ctr Macromol Chem CMaC Fac Sci Krijgslaan 281 S4 B-9000 Ghent Belgium;

    Univ Ghent Dept Appl Phys RUPT Fac Engn &

    Architecture Sint Pietersnieuwst 41 B4 B-9000 Ghent Belgium;

    Univ Ghent Dept Organ &

    Macromol Chem Supramol Chem Grp Ctr Macromol Chem CMaC Fac Sci Krijgslaan 281 S4 B-9000 Ghent Belgium;

    Univ Ghent Fac Pharmaceut Sci Dept Pharmaceut Anal LPM Ottergemsesteenweg 460 B-9000 Ghent Belgium;

    Swiss Fed Inst Technol Dept Mat Polymer Surfaces Grp Lab Surface Sci &

    Technol Vladimir Prelog Weg 5 CH-8093 Zurich Switzerland;

    Swiss Fed Inst Technol Dept Mat Polymer Surfaces Grp Lab Surface Sci &

    Technol Vladimir Prelog Weg 5 CH-8093 Zurich Switzerland;

    Univ Ghent Dept Organ &

    Macromol Chem Supramol Chem Grp Ctr Macromol Chem CMaC Fac Sci Krijgslaan 281 S4 B-9000 Ghent Belgium;

    Univ Ghent Dept Basic Med Sci Fac Med &

    Hlth Sci De Pintelaan 185 6B3 B-9000 Ghent Belgium;

    Univ Ghent Fac Pharmaceut Sci Dept Pharmaceut Anal LPM Ottergemsesteenweg 460 B-9000 Ghent Belgium;

    Univ Ghent Dept Appl Phys RUPT Fac Engn &

    Architecture Sint Pietersnieuwst 41 B4 B-9000 Ghent Belgium;

    Univ Ghent Dept Organ &

    Macromol Chem Supramol Chem Grp Ctr Macromol Chem CMaC Fac Sci Krijgslaan 281 S4 B-9000 Ghent Belgium;

    Univ Ghent Dept Appl Phys RUPT Fac Engn &

    Architecture Sint Pietersnieuwst 41 B4 B-9000 Ghent Belgium;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学工业;
  • 关键词

    plasma polymerization; 2-oxazoline; near atmospheric pressure dielectric barrier discharge; polypropylene; tissue engineering;

    机译：等离子体聚合;2-恶唑啉;近大气压介电阻挡放电;聚丙烯;组织工程;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号