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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Current Treatment of Colorectal Liver Metastasis as a Chronic Disease
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Current Treatment of Colorectal Liver Metastasis as a Chronic Disease

机译:目前治疗结直肠肝转移作为慢性病

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摘要

Background/Aim: The treatment of colorectal liver metastases is challenging and requires multidisciplinary strategies. Unfortunately, only 25% of patients with colorectal liver metastases are eligible for liver resection. Due to the variety of therapeutic approaches, this percentage has increased; however, at the same time, the definition of resectability has become complex. The aim of this review was to provide an overview of current surgical therapies for colorectal liver metastases. Materials and Methods: Relevant studies published before June 2019 were identified using PubMed. A comprehensive review of the current literature regarding the impact of and innovations in the therapy of colorectal liver metastases was carried out. Results: The major advances in the resectability of colorectal liver metastases were effective chemotherapy regimens and preoperative liver volume modulation techniques. In addition, health professionals face rapid technical developments in interventional local therapies, minimally invasive surgery, robot-assisted surgery and even liver transplantation. Conclusion: Currently, liver metastases from colorectal cancer are considered a chronic disease. In cases of advanced colorectal liver metastases, the definition of resectability and the indications for surgical treatment should be exclusively determined by experienced hepatobiliary surgeons.
机译:背景/目的:结直肠肝转移的治疗是挑战性的,需要多学科策略。不幸的是,只有25%的结肠直肠肝转移患者有资格肝切除术。由于各种治疗方法,这种百分比增加了;但是,与此同时,重新切性的定义变得复杂。本综述的目的是提供目前结直肠肝转移的手术疗法概述。材料和方法:使用PubMed确定2019年6月之前发表的相关研究。进行了关于当前文献的全面审查,了解结直肠肝转移治疗的影响和创新。结果:结肠直肠肝转移可切除性的主要进步是有效的化疗方案和术前肝脏体积调制技术。此外,卫生专业人员面临介入局部疗法,微创手术,机器人辅助手术甚至肝移植的快速技术发展。结论:目前,来自结肠直肠癌的肝转移被认为是一种慢性疾病。在晚期结肠直肠肝转移的情况下,可切除性的定义和手术治疗的适应症应由经验丰富的肝脏外科医生专门确定。

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