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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Recent Trends in HPV Infection and Type Distribution in Greece
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Recent Trends in HPV Infection and Type Distribution in Greece

机译：近期HPV感染和型分布在希腊的趋势

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摘要

Background/Aim: This study gives an insight into recent trends for Human papillomavirus (HPV)-specific infection and its fluctuation over the years 2011-2016. Materials and Methods: A total of 2,417 Caucasian women between the age of 18 and 71 years underwent their annual gynaecologic examination at the Outpatient Gynaecological Clinic in the study period. Results: Overall HPV prevalence was 43.9%, and high-risk HPV accounted for 31.3%. HPV16 was the most common high-risk type followed by HPV51 and HPV31. HPV positivity was higher in those with low- and high-grade squamous intraepithelial lesions (HSILs) than in women with a normal cytological test. HPV infection was highest in 2011.The prevalence of single infections remained higher than multiple infections over the entire study period. HPV16 prevalence was very high in the first years of the study and HPV18 exhibited highest prevalence in 2011. Younger women exhibited a significant increase in HPV infection from 2014. Overall HPV infection decreased over the study period. Conclusion: These data suggest that HPV vaccination might reduce the frequency of HSILs and cervical cancer and are useful for the development of a national screening programme.
机译：背景/目的：本研究介绍了近期人类乳头瘤病毒（HPV）的趋势（HPV）的特异性感染及其在2011 - 2016年多年来的波动。材料和方法：18岁至71岁之间的2,417名白种人妇女在研究期间在门诊妇科诊所进行了每年的GynaEconicic检查。结果：总体HPV患病率为43.9％，高风险HPV占31.3％。 HPV16是最常见的高风险类型，后跟HPV51和HPV31。在具有正常细胞学测试的女性中，HPV阳性呈低级和高级鳞状上皮病变（HSIL）的阳性阳性较高。 HPV感染于2011年最高。单一感染的患病率仍然高于整个研究期间的多重感染。研究中的第一年HPV16患病率非常高，HPV18在2011年表现出最高的流行。年龄较小的女性从2014年表现出显着增加的HPV感染。总体的HPV感染在研究期间减少。结论：这些数据表明HPV疫苗接种可能降低HSILS和宫颈癌的频率，可用于制定国家筛查计划。

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