beta-Hydroxybutyrate: A Signaling Metabolite

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beta-Hydroxybutyrate: A Signaling Metabolite

机译：β-羟基丁酸酯：信号传导代谢物

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Various mechanisms in the mammalian body provide resilience against food deprivation and dietary stress. The ketone body beta-hydroxybutyrate (BHB) is synthesized in the liver from fatty acids and represents an essential carrier of energy from the liver to peripheral tissues when the supply of glucose is too low for the body's energetic needs, such as during periods of prolonged exercise, starvation, or absence of dietary carbohydrates. In addition to its activity as an energetic metabolite, BHB is increasingly understood to have cellular signaling functions. These signaling functions of BHB broadly link the outside environment to epigenetic gene regulation and cellular function, and their actions may be relevant to a variety of human diseases as well as human aging.

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《Annual Review of Nutrition》 |2017年第2017期|共26页
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正文语种 eng
中图分类营养卫生、食品卫生;
关键词
metabolism; epigenetics; ketone bodies; fasting; aging;

机译：新陈代谢;表观生物;酮体;禁食;老化;

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beta-Hydroxybutyrate: A Signaling Metabolite

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