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Objectively measured physical activity and all cause mortality: A systematic review and meta-analysis

机译:客观测量的身体活动和所有原因死亡率:系统审查和荟萃分析

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Current physical activity recommendations have been based on evidence from systematic reviews of questionnaire-based data. Questionnaire-based physical activity data are subject to both random and non random error. If the estimated association between physical activity and health outcomes was different when a more accurate, objective measure was used, this would have important health policy implications for physical activity. We conducted a systematic review and meta-analysis of published cohort studies that investigated the association between an objective measure of physical activity and all cause mortality. We searched PubMed, Scopus, Embase, Cochrane library, and SPORTDiscus for prospective cohort studies that examined the association between objectively measured (accelerometer, pedometer, or doubly labeled water method) physical activity and mortality in adults aged >= 18 years, of either sex. Summary hazard ratios and 95% confidence interval [CI]s were computed using random-effects models. Thirty-three articles from 15 cohort studies were identified that together ascertained 3903 deaths. The mean years of follow-up ranged from 2.3-14.2 years. Individuals in the highest category of light, moderate-to-vigorous, and total physical activity had 40% (95%CI 20% to 55%), 56% (95%CI 41% to 67%), and 67% (95%CI 57% to 75%), respectively, lower risk for mortality compared to individuals in the lowest category of light, moderate-to-vigorous, and total physical activity. The summary hazard ratio for objectively measured physical activity and all cause mortality is lower than previously estimated from questionnaire based studies. Current recommendations for physical activity that are based on subjective measurement may underestimate the true reduction in mortality risk associated with physical activity.
机译:目前的体力活动建议是基于对问卷数据的系统性审查得出的证据。基于问卷调查的体力活动数据既有随机误差,也有非随机误差。如果使用更准确、客观的测量方法时,体力活动与健康结果之间的估计关联不同,这将对体力活动产生重要的健康政策影响。我们对已发表的队列研究进行了系统回顾和荟萃分析,这些研究调查了体力活动客观指标与全因死亡率之间的关系。我们在PubMed、Scopus、Embase、Cochrane library和SPORTDiscus中搜索前瞻性队列研究,这些研究检验了年龄大于等于18岁的成年人的客观测量(加速计、计步器或双标水法)体力活动与死亡率之间的关联,无论男女。使用随机效应模型计算总结危险比和95%置信区间[CI]。从15项队列研究中发现了33篇文章,共确定了3903例死亡。平均随访时间为2.3-14.2年。与轻度、中度至剧烈和总体力活动最低类别的个体相比,轻度、中度至剧烈和总体力活动最高类别的个体的死亡率分别为40%(95%可信区间20%至55%)、56%(95%可信区间41%至67%)和67%(95%可信区间57%至75%)。客观测量的体力活动和全因死亡率的汇总危险比低于之前基于问卷调查的研究估计的危险比。目前基于主观测量的体力活动建议可能低估了与体力活动相关的死亡率风险的真实降低。

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