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Effective Utilization of Oral Hypoglycemic Agents to Achieve Individualized HbA1c Targets in Patients with Type 2 Diabetes Mellitus

机译:有效利用口腔降血糖药物以达到2型糖尿病患者的个体化HBA1C靶标

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摘要

Type 2 diabetes is a progressive condition that may require the combination of three oral treatments to achieve optimal glycemic management to prevent microvascular and macrovascular complications whilst minimizing the risk of acute complications and side effects or adverse reactions to treatments. With the widening availability of treatment options and increasing importance of individualized treatment pathways, including personalized HbA1c targets, this article will explore the mode of action of currently available oral treatments, factors to consider when individualizing HbA1c targets, the relevance of estimated glomerular filtration rate assessment, and the importance of reviewing the clinical impact of all treatment decisions.
机译:2型糖尿病是一种进展性疾病,可能需要结合三种口服治疗来实现最佳血糖管理,以防止微血管和大血管并发症,同时将急性并发症、副作用或治疗不良反应的风险降至最低。随着治疗方案的日益广泛和个体化治疗途径的重要性的增加,包括个性化的HbA1c靶点,本文将探讨目前可用的口服治疗的作用方式、个体化HbA1c靶点时应考虑的因素、估计肾小球滤过率评估的相关性,以及审查所有治疗决定的临床影响的重要性。

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