Real-Time Clinical Monitoring of Biomolecules

Michelle L. Rogers; Martyn G. Boutelle

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Real-Time Clinical Monitoring of Biomolecules

机译：生物分子的实时临床监测

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Continuous monitoring of clinical biomarkers offers the exciting possibility of new therapies that use biomarker levels to guide treatment in real time. This review explores recent progress toward this goal. We initially consider measurements in body fluids by a range of analytical methods. We then discuss direct tissue measurements performed by implanted sensors; sampling techniques, including microdialysis and ultrafiltration; and noninvasive methods. A future directions section considers analytical methods at the cusp of clinical use.

机译：连续监测临床生物标志物提供了新的令人兴奋的可能性，这些新疗法利用生物标志物水平实时指导治疗。这篇评论探讨了朝着这个目标的最新进展。我们最初考虑通过多种分析方法对体液进行测量。然后，我们讨论由植入式传感器执行的直接组织测量;采样技术，包括微透析和超滤;和非侵入性方法。未来的指导部分将在临床使用中考虑分析方法。

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《Annual Review of Analytical Chemistry》 |2013年第null期|共27页
作者
Michelle L. Rogers; Martyn G. Boutelle;
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正文语种 eng
中图分类物理化学计量;
关键词
microdialysis; biosensor; human; brain; tissue; electrode;

机译：微透析;生物传感器;人;脑;组织;电极;

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专利

1. Real-Time Clinical Monitoring of Biomolecules [J] . Michelle L. Rogers, Martyn G. Boutelle Annual Review of Analytical Chemistry . 2013,第Null期

机译：生物分子的实时临床监测
2. Scattered Light Imaging Enables Real-Time Monitoring of Label-Free Nanoparticles and Fluorescent Biomolecules in Live Cells [J] . Wang Fengbang, Chen Bolei, Yan Bing, Journal of the American Chemical Society . 2019,第36期

机译：散射光成像可实时监测活细胞中无标记的纳米颗粒和荧光生物分子
3. Label-Free CMOS Bio Sensor With On-Chip Noise Reduction Scheme for Real-Time Quantitative Monitoring of Biomolecules [J] . Kim S.-J. Biomedical Circuits and Systems, IEEE Transactions on . 2012,第3期

机译：具有片上降噪方案的无标签CMOS生物传感器，用于实时定量监测生物分子
4. A Disposable Grating-integrated Multi-channel SPR Sensor Chip for Real-time Monitoring of Biomolecule Binding [C] . Young-Hyun Jin, Young-Ho Cho IEEE/LEOS International Conference on Optical MEMS and Nanophotonics . 2007

机译：一种一次性光栅集成的多通道SPR传感器芯片，用于实时监测生物分子绑定
5. Electrochemical Biosensors for Real-Time Environmental and Clinical Monitoring. [D] . Ganesana, Mallikarjunarao. 2012

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机译：集成了读出电路的浮栅互补金属氧化物半导体传感器阵列，无需表面结合即可对生物分子进行实时无标签定量监测
8. Effect of Real-time Clinical Monitoring and a 'Closed Loop' Medication System on Adverse Drug Event Detection; Final rept. 21 Sep 2006-20 Mar 2008 [R] . Mendelowitz, P. C. 2008

机译：实时临床监测和“闭环”药物治疗系统对药物不良事件检测的影响;最终的评论。 2006年9月21日至2008年3月20日

Real-Time Clinical Monitoring of Biomolecules

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