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Surface Plasmon-Coupled Emission: What Can Directional Fluorescence Bring to the Analytical Sciences?

机译:表面等离子耦合发射:定向荧光能为分析科学带来什么?

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摘要

Surface plasmon-coupled emission (SPCE) arose from the integration of fluorescence and plasmonics, two rapidly expanding research fields. SPCE is revealing novel phenomena and has potential applications in bioanalysis, medical diagnostics, drug discovery, and genomics. In SPCE, excited fluorophores couple with surface plasmons on a continuous thin metal film; plasmophores radiate into a higher-refractive index medium with a narrow angular distribution. Because of the directional emission, the sensitivity of this technique can be greatly improved with high collection efficiency. This review describes the unique features of SPCE. In particular, we focus on recent advances in SPCE-based analytical platforms and their applications in DNA sensing and the detection of other biomolecules and chemicals.
机译:表面等离子体激元耦合发射(SPCE)源于荧光和等离子体激元的集成,这是两个迅速扩展的研究领域。 SPCE正在揭示新颖的现象,并在生物分析,医学诊断,药物发现和基因组学中具有潜在的应用。在SPCE中,激发的荧光团与表面等离激元耦合在连续的薄金属膜上。质体辐射到具有窄角度分布的高折射率介质中。由于有方向性发射,该技术的灵敏度可以大大提高,并且收集效率很高。这篇评论描述了SPCE的独特功能。特别是,我们专注于基于SPCE的分析平台的最新进展及其在DNA传感以及其他生物分子和化学物质检测中的应用。

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