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首页> 外文期刊>Annals of epidemiology >Sex-race differences in the relationship between obesity and asthma: the behavioral risk factor surveillance system, 2000.
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Sex-race differences in the relationship between obesity and asthma: the behavioral risk factor surveillance system, 2000.

机译：肥胖与哮喘之间的性别差异：行为危险因素监测系统，2000年。

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PURPOSE: Although prospective data are limited, recent cross-sectional studies support obesity as a cause of asthma. They also suggest that the association is present only among women. Our analysis examines possible sex-race differences in the relationship between obesity and asthma. METHODS: We examined data from the 2000 Behavioral Risk Factor Surveillance System. To minimize diagnostic bias, the sample was limited to adults aged 18 to 34 years. All cases had doctor-diagnosis of asthma and ongoing symptoms. Multiple logistic regression was used to examine risk factors for current asthma vs. never having asthma. RESULTS: Obesity and asthma were more strongly related among women than men (test for interaction, p<0.01). Across increasing categories of body mass index (BMI), we observed a dose-response relationship among women (odds ratios: 0.9, 1.0 [reference], 1.0, 1.3, 1.5, 1.8, and 3.2) but only a non-significant increased risk in severely obese men (odd ratio: 2.0). In subgroup analyses, however, the obesity-asthma association was present in four of six sex-race/ethnicity subgroups, including black and Hispanic men. CONCLUSIONS: Although the obesity-asthma association is stronger among women than men, our analysis demonstrates a strong positive association among men from minority groups. These race-specific results may help explain some of the "inconsistencies" in prior studies.
机译：目的：尽管前瞻性数据有限，但最近的横断面研究支持肥胖是哮喘的病因。他们还建议该关联仅在女性中存在。我们的分析检查了肥胖与哮喘之间可能存在的性别差异。方法：我们检查了来自2000年行为危险因素监视系统的数据。为了最大程度地减少诊断偏差，该样本仅限于18至34岁的成年人。所有病例均经医生诊断为哮喘并伴有症状。多元logistic回归用于检查当前哮喘与从未患哮喘的危险因素。结果：肥胖和哮喘在女性中比男性更紧密（相互作用测试，p <0.01）。在不断增加的体重指数（BMI）类别中，我们观察到女性之间的剂量反应关系（几率：0.9、1.0 [参考]，1.0、1.3、1.5、1.8和3.2），但风险无明显增加在严重肥胖的男性中（比值：2.0）。但是，在亚组分析中，肥胖与哮喘的关联存在于六个性别，种族/族裔亚组中的四个，包括黑人和西班牙裔男子。结论：尽管女性的肥胖-哮喘关联性强于男性，但我们的分析表明，少数族裔的男性与男性之间存在强烈的正相关性。这些针对种族的结果可能有助于解释先前研究中的某些“矛盾之处”。

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