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首页> 外文期刊>Annals of epidemiology >The impact of maternal anemia on perinatal mortality: a population-based, prospective cohort study in China.
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The impact of maternal anemia on perinatal mortality: a population-based, prospective cohort study in China.

机译：产妇贫血对围产期死亡率的影响：中国一项基于人群的前瞻性队列研究。

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PURPOSE: To evaluate whether anemia during pregnancy is associated with increased risk of stillbirth and neonatal death. METHODS: A prospective cohort study, using data from a population-based pregnancy-monitoring system in 13 counties in East China (1993-1996) was conducted. Singleton live births (n=163,313) and stillbirths (n=1,354) delivered at 20 to 44 weeks to women with one or more hemoglobin measures during pregnancy were included. Stillbirth and neonatal mortality rates by anemia status in each trimester were estimated. Multivariable Cox proportional hazards regression models were used to evaluate the association between hemoglobin levels and mortality risk. RESULTS: The stillbirth rates were 6.2 and 9.2 per 1,000 births in women with and without anemia (hemoglobin < 10 g/dL), respectively. The protective effect of anemia was mainly in the third trimester. Hemoglobin of 9 g/dL in the third trimester was associated with reduced risk (hazard ratio [HR], 0.8; 95% confidence interval [CI], 0.7-0.97). Maternal anemia was not associated with neonatal mortality. CONCLUSIONS: Although maternal anemia was not associated with increased risk of mortality in the neonatal period, women with anemia during the third trimester had lower risk of stillbirth.
机译：目的：评估妊娠期贫血是否与死产和新生儿死亡风险增加有关。方法：采用前瞻性队列研究，利用来自华东13个县（1993-1996年）的基于人口的妊娠监测系统的数据。包括在妊娠20到44周时分娩一种或多种血红蛋白的妇女的单胎活产（n = 163,313）和死胎（n = 1,354）。估计每个孕期贫血的死产和新生儿死亡率。使用多变量Cox比例风险回归模型评估血红蛋白水平与死亡风险之间的关联。结果：贫血和无贫血（血红蛋白<10 g / dL）的妇女的死胎率分别为每1000胎6.2和9.2。贫血的保护作用主要在妊娠中期。妊娠中期9 g / dL的血红蛋白与降低的风险相关（危险比[HR]为0.8; 95％置信区间[CI]为0.7-0.97）。产妇贫血与新生儿死亡率无关。结论：尽管孕妇贫血与新生儿期死亡风险增加无关，但妊娠晚期贫血妇女死产风险较低。

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