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首页> 外文期刊>Annals of epidemiology >Invasive disease caused by Haemophilus influenzae: the sensitivity of statutory reporting.
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Invasive disease caused by Haemophilus influenzae: the sensitivity of statutory reporting.

机译：流感嗜血杆菌引起的侵袭性疾病：法定报告的敏感性。

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PURPOSE: The objective of the study was to investigate the sensitivity of the statutory reporting of Haemophilus influenzae invasive disease (HIID) during the period between 1996 and 1997 in Catalonia, Spain. METHODS: The incidence of HIID reported passively by clinicians was compared with the cases detected by a system of microbiological surveillance. In all cases isolated, the age of the patient, the clinical form and the serotype were investigated. RESULTS: Sixty-six cases were passively reported and 111 were detected by microbiological surveillance. Overall sensitivity of reporting was 59.5% (95% CI, 50.7-69.1), with differences being observed according to the variables studied. The highest values were obtained in children under 5 years (87.8%; 95% CI, 73.7-95.9), in cases with meningitis and/or sepsis (64.3%; 95% CI, 50.4-76.6) and in serotype b (73.0%; 95% CI, 60.3-83.4). In the logistical regression analysis, only age under 5 years was associated with greater reporting (OR= 9.8; 95% CI, 2.5-37.8). CONCLUSIONS: Reported morbidity in children under 5 years is a good estimate of the true incidence of HIID in Catalonia (underreporting was 12.2%), but not for those above this age in whom the underreporting was 57.2%.
机译：目的：本研究的目的是调查西班牙加泰罗尼亚1996年至1997年期间流感嗜血杆菌侵袭性疾病（HIID）法定报告的敏感性。方法：将临床医生被动报告的HIID发生率与通过微生物监测系统检测到的病例进行比较。在所有隔离的病例中，研究了患者的年龄，临床形式和血清型。结果：通过微生物监测被动报告66例，检出111例。报告的总体敏感性为59.5％（95％CI，50.7-69.1），根据研究的变量观察到差异。 5岁以下儿童（87.8％; 95％CI，73.7-95.9），脑膜炎和/或脓毒症（64.3％; 95％CI，50.4-76.6）和b型血清（73.0％）的儿童中获得最高值; 95％CI，60.3-83.4）。在逻辑回归分析中，只有5岁以下的年龄与更大的报告相关（OR = 9.8; 95％CI，2.5-37.8）。结论：5岁以下儿童的发病率是加泰罗尼亚HIID真实发生率的良好估计（漏报率为12.2％），但低于该年龄段的儿童的漏报率为57.2％。

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